The presents study aimed to prepare and characterize
Solid Lipid Nanoparticles (SLNs) from palm oil materials. Hydrogenated
palm oil and lecithin incorporated with surfactant were mixed and formed
by High Pressure Homogenization (HPH) at elevated temperature. Appropriate
analytical methods are needed for the characterization of SLN. The use
of several analytical techniques is a necessity such as particle size
which determined using Photon Correlation Spectroscopy (PCS). The change
of particle charge was studied by Zeta Potential (ZP) measurements, while
the melting and recrystallization behavior characterized by Differential
Scanning Calorimetry (DSC). Data showed physical stability of the formulation.
In conclusion, the SLN presented here are well suited for several applications
including drug delivery.