Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Pakistan Journal of Nutrition
  Year: 2006 | Volume: 5 | Issue: 5 | Page No.: 410-413
DOI: 10.3923/pjn.2006.410.413
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail
Effects of Aqueous Leaf Extract of Pride of Barbados (Caesalpina pulcherrima) on the Activities of Some Liver Function Enzymes and Blood Glucose Concentration in Normal Rabbits
T. P. Prohp , A.O. Madusha , I.O. Onoagbe , U. Inegbenebor and R. I. Okoli

Abstract:
Some of the effects of the aqueous leaf extract of Pride of Barbados (Caesalpina pulcherrima) on the activities of plasma glutamic pyruvate transaminase (GPT), glutamic oxaloacetate transaminase (GOT), acid phosphatase (AP), alkaline phosphatase (ALP) and blood glucose concentration in normal rabbits were carried out. All the rabbits used which were of New Zealand strain weighed between 1.00 to 1.60 kg. About 100ml aqueous leaf extract of this plant was administered daily to the test rabbits orally through clean drinking troughs for a period of 15 days. Analyses were conducted using the blood collected intravenously from the larger veins at the back of the ears of rabbits. Aqueous leaf extract of Pride of Barbados did not affect plasma GOT, GPT, AP and ALP activities (P > 0.05). However, plasma glucose concentration increased significantly (P < 0.05) on the 9th, 11th, 13th and 15th days of administration of the aqueous leaf extract to the rabbits. It might be unsafe to abuse the use of this extract as liver tonic as it may create serious health problems for the diabetics due to the likely escalation of complications arising from hyperglycemia. Non – diabetics however, may be placed on a routine check of their fasting blood sugar as they use the aqueous leaf extract of Pride of Barbados.
PDF Citation Report Citation
 RELATED ARTICLES:
  •    Anti - Diabetic Properties and Toxicological Studies of Triplochiton scleroxylon on the Heart Enzymes in Normal and Streptozotocin - induced Diabetic Rabbits
  •    Anti - Diabetic Properties and Toxicological Studies of Triplochiton scleroxylon on the Liver Enzymes in Normal and Streptozotocin - induced Diabetic Rabbits
How to cite this article:

T. P. Prohp , A.O. Madusha , I.O. Onoagbe , U. Inegbenebor and R. I. Okoli , 2006. Effects of Aqueous Leaf Extract of Pride of Barbados (Caesalpina pulcherrima) on the Activities of Some Liver Function Enzymes and Blood Glucose Concentration in Normal Rabbits . Pakistan Journal of Nutrition, 5: 410-413.

DOI: 10.3923/pjn.2006.410.413

URL: https://scialert.net/abstract/?doi=pjn.2006.410.413

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

       

       

Curve Bottom