
	Journal of Biological Sciences
	Year: 2007 \| Volume: 7 \| Issue: 3 \| Page No.: 582-584 DOI: 10.3923/jbs.2007.582.584

Effects of Ethanolic Extract of Capparis aphylla (Roth.) on Testicular Steroidogenesis in Rats

I. Sarathchandiran, R. Manavalan, M.A. Akbarsha, B. Kadalmani and P.K. Karar

Abstract: Ethanol extract of Capparis aphylla (Roth.) whole plant (EECA) was evaluated for possible testicular antisteroidogenic activity in mature male rat. The ethanol extract at the doses of 50, 100 and 200 mg kgG¹ body weight (i.p) arrested the testicular steroidogenisis. The cholesterol and ascorbic acid content in testis were significantly elevated in treated rat. The extract also significantly inhibited the activity of Δ⁵-3β-hydroxy steroid dehydrogenase (Δ⁵-3β-HSD) and glucose-6-phosphate dehydrogenase (G-6-PD), the two key enzymes involved in testicular steroidogenesis. Results of this study suggested that the ethanol extract of whole plant of Capparis aphylla (Roth.) acts as an testicular antisteroidogenic agent.

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How to cite this article:

I. Sarathchandiran, R. Manavalan, M.A. Akbarsha, B. Kadalmani and P.K. Karar, 2007. Effects of Ethanolic Extract of Capparis aphylla (Roth.) on Testicular Steroidogenesis in Rats. Journal of Biological Sciences, 7: 582-584.

DOI: 10.3923/jbs.2007.582.584

URL: https://scialert.net/abstract/?doi=jbs.2007.582.584

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