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Journal of Biological Sciences

Year: 2007 | Volume: 7 | Issue: 3 | Page No.: 582-584
DOI: 10.3923/jbs.2007.582.584

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Authors


I. Sarathchandiran


R. Manavalan


M.A. Akbarsha


B. Kadalmani


P.K. Karar


Keywords


  • Δ5-3ß-HSD
  • antifertility
  • ascorbic acid
  • Capparis aphylla
  • cholesterol
  • G-6-PD
  • testicular steroidogenesis
Research Article

Effects of Ethanolic Extract of Capparis aphylla (Roth.) on Testicular Steroidogenesis in Rats

I. Sarathchandiran, R. Manavalan, M.A. Akbarsha, B. Kadalmani and P.K. Karar
Ethanol extract of Capparis aphylla (Roth.) whole plant (EECA) was evaluated for possible testicular antisteroidogenic activity in mature male rat. The ethanol extract at the doses of 50, 100 and 200 mg kgG1 body weight (i.p) arrested the testicular steroidogenisis. The cholesterol and ascorbic acid content in testis were significantly elevated in treated rat. The extract also significantly inhibited the activity of Δ5-3β-hydroxy steroid dehydrogenase (Δ5-3β-HSD) and glucose-6-phosphate dehydrogenase (G-6-PD), the two key enzymes involved in testicular steroidogenesis. Results of this study suggested that the ethanol extract of whole plant of Capparis aphylla (Roth.) acts as an testicular antisteroidogenic agent.
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How to cite this article

I. Sarathchandiran, R. Manavalan, M.A. Akbarsha, B. Kadalmani and P.K. Karar, 2007. Effects of Ethanolic Extract of Capparis aphylla (Roth.) on Testicular Steroidogenesis in Rats. Journal of Biological Sciences, 7: 582-584.

DOI: 10.3923/jbs.2007.582.584

URL: https://scialert.net/abstract/?doi=jbs.2007.582.584

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