Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Pakistan Journal of Biological Sciences
  Year: 2015 | Volume: 18 | Issue: 1 | Page No.: 46-49
DOI: 10.3923/pjbs.2015.46.49
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Acute and Cytotoxicity Studies of Aqueous and Ethanolic Leaf Extracts of Chromolaena odorata

R.N. Asomugha, A.N. Ezejiofor, P.N. Okafor and I.I. Ijeh

Abstract:
Chromolaena odorata, a commonly used traditional remedy for different ailments, believed to be quite safe in terms of toxicity was evaluated for acute toxicity and cytotoxic potentials. Acute toxicity was done on albino Wistar rats using the Lorke method while brine shrimps were used to test for cytotoxicity. The results showed that the estimated LD50 for the aqueous and ethanolic extracts was 2154 and >5000 mg kg-1 body weight, respectively. Cytotoxicity to brine shrimps showed LC50 values of 324 and 392 ppm for aqueous and ethanolic extracts, respectively. These results indicate the relative non toxic nature of Chromolaena odorata extracts.
PDF Fulltext XML References Citation Report Citation
How to cite this article:

R.N. Asomugha, A.N. Ezejiofor, P.N. Okafor and I.I. Ijeh, 2015. Acute and Cytotoxicity Studies of Aqueous and Ethanolic Leaf Extracts of Chromolaena odorata. Pakistan Journal of Biological Sciences, 18: 46-49.

DOI: 10.3923/pjbs.2015.46.49

URL: https://scialert.net/abstract/?doi=pjbs.2015.46.49

COMMENTS
02 October, 2016
Nguyen Tam:
Hello
I am a chemistry teacher in Vietnam
I have read through the article about your research.
"Acute and Cytotoxicity Studies of Aqueous Extracts of Chromolaena and Ethanolic Leaf odorata"
It was great, I have found a lot of information from it.

If you do not mind, could you please give me more information about your research. I need to refer it to guide a group of students to do scientific research.

I think the results from this study will help us find some valuable medicinal products.

Thank you very much!
(Forgive me for using "google translate" to write to you)
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 
 
 

Curve Bottom