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Pakistan Journal of Biological Sciences
  Year: 2007 | Volume: 10 | Issue: 23 | Page No.: 4236-4240
DOI: 10.3923/pjbs.2007.4236.4240
 
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The Effect of Equisetum arvense L. (Equisetaceae) in Histological Changes of Pancreatic β-Cells in Streptozotocin-Induced Diabetic in Rats
Safiyeh Soleimani, Fathallah Fathi Azarbaizani and Vahid Nejati

Abstract:
In view of alleged, the methanolic extract of Equisetum arvense was analysed for its antidiabetic activity in streptozotocin-induced diabetic rats. The blood glucose lowering activity of the methanolic extract was determined in streptozotocin-induced (50 mg kg-1, i.p.; dissolved in normal saline) diabetic rats, after oral administration in doses of 50 and 250 mg kg-1 daily for 5 weeks. The data was compare statistically using one-way ANOVA tukey test. The results showed methanolic extract of Equisetum arvense produced a significant antidiabetic activity at doses 50 and 50 mg kg-1/b.wt. Concurrent histological studies of the pancreas of these animals showed comparable regeneration by methanolic extract which were earlier, necrosed by streptozotocin.
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How to cite this article:

Safiyeh Soleimani, Fathallah Fathi Azarbaizani and Vahid Nejati , 2007. The Effect of Equisetum arvense L. (Equisetaceae) in Histological Changes of Pancreatic β-Cells in Streptozotocin-Induced Diabetic in Rats. Pakistan Journal of Biological Sciences, 10: 4236-4240.

DOI: 10.3923/pjbs.2007.4236.4240

URL: https://scialert.net/abstract/?doi=pjbs.2007.4236.4240

 
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