Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Journal of Biological Sciences
  Year: 2010 | Volume: 10 | Issue: 5 | Page No.: 455-459
DOI: 10.3923/jbs.2010.455.459
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Silk Fibroin/Gelatin Hybrid Films for Medical Applications: Study on Chlorhexidine Diacetate

Simchuer Wilaiwan, Srisuwan Yaowalak, Baimark Yodthong and Srihanam Prasong

Abstract:
This study aimed to prepare silk fibroin (SF)/gelatin (G) hybrid films by a solvent evaporation method for loading chlorhexidine diacetate (CHX). The SF and G solution in different ratios were mixed with CHX and placed on the 5 cm polystyrene plates before drying to obtain hybrid films. The films were determined their secondary structures and thermal properties by using Fourier transform infrared (FT-IR) spectrometer and thermogravimetric analysis (TGA), respectively. The results found that all of film composed of α-helix and β-sheet structures. However, differences of the α-helix and β-sheet structures were differed according to each component. The hybrid films showed soft texture and decreased of brittle compared to SF film only when the G content increased. Thermal properties of the films indicated that decomposition temperature profiles of all films did not differ dramatically, however, combination of characteristics both SF and G were appeared in hybrid films. The releasing rate of CHX-loaded in the films was found that the CHX has released from the SF film in higher rate than hybrid and G films, respectively. It is a promising that polarity, flexibility as well as component ratio of each polymer play important role on the releasing of CHX.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Dissolution Properties of Silk Cocoon Shells and Degummed Fibers from African Wild Silkmoths
  •    Recent Advances in Novel Drug Delivery System Through Gels: Review
  •    The Effect of Temperatures and Incubation Times on Some Properties of Silk Fibroin/Chitosan Blend Films
  •    Characterization of Tetracycline-loaded Thai Silk Fibroin/Gelatin Blend Films
  •    Silk Fibroin Film Loaded Chlorhexidine Diacetate: Interaction and Characteristics
  •    Morphology, Secondary Structure and Thermal Properties of Silk Fibroin/Gelatin Blend Film
How to cite this article:

Simchuer Wilaiwan, Srisuwan Yaowalak, Baimark Yodthong and Srihanam Prasong, 2010. Silk Fibroin/Gelatin Hybrid Films for Medical Applications: Study on Chlorhexidine Diacetate. Journal of Biological Sciences, 10: 455-459.

DOI: 10.3923/jbs.2010.455.459

URL: https://scialert.net/abstract/?doi=jbs.2010.455.459

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 

Curve Bottom