Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
International Journal of Pharmacology
  Year: 2014 | Volume: 10 | Issue: 8 | Page No.: 461-469
DOI: 10.3923/ijp.2014.461.469
Antioxidant and Antimutagenic Potential of Seeds and Pods of Green Cardamom (Elettaria cardamomum)
Asma Saeed, Bushra Sultana, Farooq Anwar, Muhammad Mushtaq, Khalid M. Alkharfy and Anwarul-Hassan Gilani

Abstract:
The present study reports the antioxidant and antimutaganic potential of the aqueous (30 and 70%) and acidified (0.5 and 1 N) methanolic extracts from seeds and pods of green cardamom (Elettaria cardamomum). The Total Phenolic Compounds (TPC) of extracts were determined by Follin-Ciocalteu reagent. Antioxidant activity of the extracts produced was evaluated by the measurements of 2, 2,-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and percentage inhibition of linoleic acid peroxidation method, whereas mutagenic and antimutagenic activities were assessed using Ames bacterial test. The TPC, scavenging of DPPH° and inhibition of linoleic acid were found to be 27.75-126.35 mg gallic acid equivalent g-1 DW, 46-91% at 5 mg L-1 of extract concentration and 34-83%, respectively. Furthermore, the extracts of seeds and pods of green cardamom showed strong antimutagenic potential against mutant strains S. typhimurium TA98 and S. typhimurium TA100 while none of the extract showed mutagenicity. The results of this study support that the extracts from cardamom seeds and pods can be explored as potential chemotherapeutic agents against cancer as well as for the pharmaceutical and nutraceutical applications.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Citrullus lanatus Extract Reverses Oxidative and Haematological Dysfunction in Carbon Tetrachloride Induced Liver Damaged Rats
  •    Variation in Antioxidant Activity and Phenolic and Flavonoid Contents in the Flowers and Leaves of Ghaneri (Lantana camara L.) as Affected by Different Extraction Solven
  •    A Systematic Review about Effects of Aerial Portions of Urtica dioica (Nettle) on Some Cardiovascular Risk Factors in Diabetes Mellitus
  •    Antioxidants: Their Role in Health and Disease
How to cite this article:

Asma Saeed, Bushra Sultana, Farooq Anwar, Muhammad Mushtaq, Khalid M. Alkharfy and Anwarul-Hassan Gilani, 2014. Antioxidant and Antimutagenic Potential of Seeds and Pods of Green Cardamom (Elettaria cardamomum). International Journal of Pharmacology, 10: 461-469.

DOI: 10.3923/ijp.2014.461.469

URL: https://scialert.net/abstract/?doi=ijp.2014.461.469

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 
 

       

       

Curve Bottom