Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
International Journal of Pharmacology
  Year: 2005 | Volume: 1 | Issue: 1 | Page No.: 9-16
DOI: 10.3923/ijp.2005.9.16
Future Drugs for Treatment of Acute Respiratory Distress Syndrome
Afsaneh Vazin , Mojtaba Mojtahedzadeh , Ebrahim Salehifar , Noushin Rastkari , Siavash Khalaj , Ali Rezaie and Mohammad Abdollahi

Abstract:
The acute respiratory distress syndrome (ARDS) is a common clinical disorder characterized by injury to the alveolar epithelial and endothelial barriers of the lung, acute inflammation and pro rich pulmonary edema leading to acute respiratory failure. Knowledge of the pathophysiology and management of ARDS has been improved immensely since its original description. But pharmacotherapies have not been hopeful in treatment of ARDS in clinical trials. Mortality from ARDS has decreased in certain centers over the last 10 years due to advances in supporting critically ill patients. This trend may open the window of opportunity for pharmacological manipulation of ARDS. This study reviews conventional and new treatment challenges like use of nitric oxide nebulizer, prostacycline, surfactants, anti-inflammatory agents, antioxidants, phosphodiesterase inhibitors, immunonutrients, prostaglandin E1, anti-interleukins and inhibitors of thromboxanes and leucotriens
PDF References Citation Report Citation
 RELATED ARTICLES:
  •    Place of Iron Chelators Like Desferrioxamine and Deferasirox in Management of Hyperoxia-induced Lung Injury; A Systematic Review
How to cite this article:

Afsaneh Vazin , Mojtaba Mojtahedzadeh , Ebrahim Salehifar , Noushin Rastkari , Siavash Khalaj , Ali Rezaie and Mohammad Abdollahi , 2005. Future Drugs for Treatment of Acute Respiratory Distress Syndrome. International Journal of Pharmacology, 1: 9-16.

DOI: 10.3923/ijp.2005.9.16

URL: https://scialert.net/abstract/?doi=ijp.2005.9.16

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 
 

       

       

Curve Bottom