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International Journal of Cancer Research
  Year: 2010 | Volume: 6 | Issue: 1 | Page No.: 27-34
DOI: 10.3923/ijcr.2010.27.34
 
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Anti-Cancer Effect of Indirubin-3'-Monoxime for Human Laryngeal Carcinoma

K. Paulkumar, R. Arunachalam, R. Kameswaran, R. Ramanibai and G. Annadurai

Abstract:
The present investigation made in documenting the in vitro anti-proliferative activity of indirubin-3’-monoxime on human epithelial larynx cell line (Hep-2 cells). The Indirubin propensity for anti-proliferative effects was studied and its mechanism of action was documented using the techniques Trypan blue staining, MTT assay and propidium iodide staining. We observed a dose dependent cell death on treatment with indirubin-3-monoxime. On the basis of results, we concluded, indirubin-3’-monoxime inhibits the proliferation of Human laryngeal cancer cells (Hep-2).
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How to cite this article:

K. Paulkumar, R. Arunachalam, R. Kameswaran, R. Ramanibai and G. Annadurai, 2010. Anti-Cancer Effect of Indirubin-3'-Monoxime for Human Laryngeal Carcinoma. International Journal of Cancer Research, 6: 27-34.

DOI: 10.3923/ijcr.2010.27.34

URL: https://scialert.net/abstract/?doi=ijcr.2010.27.34

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