Ethephon (etherel) is a widely used as a plant growth promoter at low doses and a herbicide at high doses was evaluated for its toxigenic effects on albino mice. The study was assessed using 3 parameters, nucleic acids (DNA and RNA) concentrations in the liver and testis, protein content and cholinesterase activity in blood plasma. Ethephon was administrated to albino mice male with three doses level (1/4, 1/8 and 1/10 LD50 mg kg-1). Ethephon was found to reduce the DNA and RNA concentrations. Similar results were observed for the protein content and cholinesterase enzyme activity. The results showed that ethephon could be a mutagenic in mice. It is recommended that a great attention should be paid towards the mutagenicity of ethephon to animals and human.
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Nada H.A. Al-Twaty, 2006. Mutagenic Effects of Ethephon on Albino Mice. Journal of Biological Sciences, 6: 1041-1046.
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