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Research Journal of Medicinal Plants

Year: 2012 | Volume: 6 | Issue: 6 | Page No.: 449-455
Research Article

Antidiabetic Effects of Fenugreek (Trigonella foenum-graecum) Seeds in the Domestic Rabbit (Oryctolagus cuniculus)

Abdalla M. Abdelatif
Department of Physiology, Faculty of Veterinary Medicine, University of Khartoum, Sudan
Mariam Y. Ibrahim
Faculty of Medicine, Omdurman Islamic University, Sudan
Amal S. Mahmoud
Faculty of Medicine, University of Khartoum, Sudan
Adult male rabbits were used to evaluate the effects of supplementation with fenugreek seeds on Body Weight (BW), plasma glucose and serum levels of cholesterol and insulin in alloxan-induced diabetic and in non-diabetic rabbits. Diabetic and non-diabetic groups of rabbits supplemented with fenugreek showed a slight increase in BW. Supplementation with fenugreek resulted in a significant decrease in glucose level of diabetic group of rabbits and a slight effect in non-diabetic rabbits. Diabetic groups of rabbits had significantly higher serum cholesterol levels compared to non-diabetic groups. Supplementation with fenugreek lowered the cholesterol level slightly in diabetic groups. The alloxan-treated groups of rabbits maintained significantly lower serum insulin level compared to the respective values obtained for the non-diabetic groups. Supplementation with fenugreek slightly increased serum insulin level in diabetic rabbits. The findings demonstrate the antidiabetic and insulin mimetic effects of fenugreek seeds in rabbits.
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Abdalla M. Abdelatif, Mariam Y. Ibrahim and Amal S. Mahmoud, 2012. Antidiabetic Effects of Fenugreek (Trigonella foenum-graecum) Seeds in the Domestic Rabbit (Oryctolagus cuniculus). Research Journal of Medicinal Plants, 6: 449-455.

URL: https://scialert.net/abstract/?doi=rjmp.2012.449.455

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