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Research Journal of Medicinal Plants
  Year: 2012 | Volume: 6 | Issue: 6 | Page No.: 449-455
DOI: 10.3923/rjmp.2012.449.455
 
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Antidiabetic Effects of Fenugreek (Trigonella foenum-graecum) Seeds in the Domestic Rabbit (Oryctolagus cuniculus)

Abdalla M. Abdelatif, Mariam Y. Ibrahim and Amal S. Mahmoud

Abstract:
Adult male rabbits were used to evaluate the effects of supplementation with fenugreek seeds on Body Weight (BW), plasma glucose and serum levels of cholesterol and insulin in alloxan-induced diabetic and in non-diabetic rabbits. Diabetic and non-diabetic groups of rabbits supplemented with fenugreek showed a slight increase in BW. Supplementation with fenugreek resulted in a significant decrease in glucose level of diabetic group of rabbits and a slight effect in non-diabetic rabbits. Diabetic groups of rabbits had significantly higher serum cholesterol levels compared to non-diabetic groups. Supplementation with fenugreek lowered the cholesterol level slightly in diabetic groups. The alloxan-treated groups of rabbits maintained significantly lower serum insulin level compared to the respective values obtained for the non-diabetic groups. Supplementation with fenugreek slightly increased serum insulin level in diabetic rabbits. The findings demonstrate the antidiabetic and insulin mimetic effects of fenugreek seeds in rabbits.
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How to cite this article:

Abdalla M. Abdelatif, Mariam Y. Ibrahim and Amal S. Mahmoud, 2012. Antidiabetic Effects of Fenugreek (Trigonella foenum-graecum) Seeds in the Domestic Rabbit (Oryctolagus cuniculus). Research Journal of Medicinal Plants, 6: 449-455.

DOI: 10.3923/rjmp.2012.449.455

URL: https://scialert.net/abstract/?doi=rjmp.2012.449.455

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