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Research Journal of Medicinal Plants

Year: 2012 | Volume: 6 | Issue: 3 | Page No.: 281-285
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Authors

Samia H. Abdelrahman

Israa M. Mousa

Salwa M.E. Khojali

A.A. Ismail

Keywords

Trypanosoma evansi causes camel Trypanosomosis. Cannabis sativa was evaluated in vivo against trypanosoma evansi experimentally infected in rats. Six groups of 6 rats each aged 6-8 weeks were used. Aqueous and methanolic extracts of the whole plant were administered orally at dose rates of 125 and 250 mg kg-1 BW for 10 consecutive days. The results were compared to the standard drug Trypacide (quinapyramine) . The parasitaemia in each rat was followed for 60 days. Both aqueous and methanolic extracts cleared the parasite on the second day of treatment for the dose 125 and 250 mg kg-1 BW. Relapse occurred at day 48 of treatment for both doses of methanolic extract. The pasitaemia appeared after 18 days of treatment with 125 mg kg-1 BW water extract. Trypacide, the standard drug curred the parasite for 10 days only were relapse occurred at day 11. The objective of this study is to evaluate trypanocidal activity of certain plant extracts compared to standard drugs.
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Samia H. Abdelrahman, Israa M. Mousa, Salwa M.E. Khojali and A.A. Ismail, 2012. Trypanocidal Effect of Cannabis sativa on Experimental Camel Trypansomosis. Research Journal of Medicinal Plants, 6: 281-285.

URL: https://scialert.net/abstract/?doi=rjmp.2012.281.285

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