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Trends in Medical Research
  Year: 2017 | Volume: 12 | Issue: 1 | Page No.: 14-19
DOI: 10.3923/tmr.2017.14.19
Effect of Radioiodine (I–131) to TSH, T3 and FT4 Hormone Levels in Hyperthyroidism High Uptake Patients
Priatna , Euis Reni Yuslianti, Sophia Nova and Basuki Hidayat

Abstract:
Background: Thyroid hormones have an important role for the body metabolism. Hyperthyroidism is a condition when thyroid hormone increases due to abnormalities in thyroid gland. Hyperthyroidism is a second largest endocrine disease in Indonesia, some risk factors that aggravate age, gender and smoking. Radioiodine (I–131) is one of the effective therapies for high uptake hyperthyroidism. Objective: The purpose of this study is to determine characteristics and therapeutic effect of radioiodine (I–131) to TSH, T3 and FT4 hormone levels hyperthyroidism high uptake patients in Nuclear Medicine Department, Dr. Hasan Sadikin Hospital Bandung, Indonesia 2014-2015 periods. Materials and Methods: This study was analytic with cross sectional design. Data obtained from 234 hyperthyroid patient’s medical records. The data was statistically analyzed with Wilcoxon test. Results: The results showed that hyperthyroidism high uptake occurred at young adult and in women patients, hyperthyroid patients had a history of taking antithyroid drugs before radioiodine therapy and radioiodine (I–131) therapeutic dose was mostly given 8 mCi. Hormone level of TSH had increased but T3, FT4 had decreased and FT4 hormone levels before and after therapy has significant difference (p<0.005). Conclusion: Radioiodine (I–131) was one of the effective therapies for high uptake hyperthyroidism patients.
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How to cite this article:

Priatna , Euis Reni Yuslianti, Sophia Nova and Basuki Hidayat, 2017. Effect of Radioiodine (I–131) to TSH, T3 and FT4 Hormone Levels in Hyperthyroidism High Uptake Patients. Trends in Medical Research, 12: 14-19.

DOI: 10.3923/tmr.2017.14.19

URL: https://scialert.net/abstract/?doi=tmr.2017.14.19

 
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