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Trends in Medical Research
  Year: 2014 | Volume: 9 | Issue: 2 | Page No.: 98-106
DOI: 10.3923/tmr.2014.98.106
 
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Value of First-day Serum Bilirubin Measurement in Predicting the Development of Neonatal Hyperbilirubinemia

Mohammad M. Mazahy, Hany A. Elkhalegy, Tarek M. Emran and Rania Ahmad Abdelhady

Abstract:
To determine the value of first day serum bilirubin level in prediction of subsequent development of significant hyperbilirubinemia in the newborn population. It was conducted during the period from August 2011-2012. One hundred healthy newborns were enrolled in the study. Serum bilirubin was estimated for all enrolled cases within the first day of life. Babies were followed up clinically for the appearance and progression of jaundice daily up to the fifth day of life. Jaundice was clinically detected in 74 (74%) newborn. The best cut off value of Total Serum Bilirubin (TSB) at the first day in predicting jaundice was 2.7 mg dL-1. The first day TSB of neonates who developed jaundice was significantly higher than those who didn’t develop jaundice (4.1, 2.3 mg dL-1, respectively). Significant hyperbilirubinemia was presented in 9 (9%) of cases. The mean first day TSB level was higher in cases with significant jaundice than that of neonates without significant jaundice (7.4, 3.3 mg dL-1, respectively). The best cut off value of TSB at first day in predicting significant hyperbilirubinemia was 6 with a sensitivity of 100.0% and specificity of 100.0%. Based on results of the present study, first day measurements of total serum bilirubin is a good predictor of significant development of hyperbilirubinemia in the subsequent days. The cutoff point is 6 mg dL-1 in the first day.
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How to cite this article:

Mohammad M. Mazahy, Hany A. Elkhalegy, Tarek M. Emran and Rania Ahmad Abdelhady, 2014. Value of First-day Serum Bilirubin Measurement in Predicting the Development of Neonatal Hyperbilirubinemia. Trends in Medical Research, 9: 98-106.

DOI: 10.3923/tmr.2014.98.106

URL: https://scialert.net/abstract/?doi=tmr.2014.98.106

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