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Research Journal of Phytochemistry
  Year: 2018 | Volume: 12 | Issue: 1 | Page No.: 14-20
DOI: 10.3923/rjphyto.2018.14.20
Structural Characterization and Anti-Diabetic Activity of Polysaccharides from Agaricus bisporus Mushroom
Periyanan Muni Raj Kumar, Moorthy Saravana Kumar, Arumugam Manivel and Shanmugavadivelu Chandra Mohan

Abstract:
Background and Objective: Mushroom polysaccharides have many health benefits. This study aimed to extract and purify polysaccharides from edible mushroom and to investigate its in vitro antidiabetic activity. Materials and Methods: Agaricus bisporus (A. bisporus ) mushroom samples were collected at Thanjavur, Tamil Nadu. Extracted polysaccharides were characterized by 1H NMR, 13C NMR spectroscopy and the in vitro antidiabetic activity of the extracted polysaccharides was analyzed by α-amylase inhibitory activity. All data were expressed as mean standard deviations (SD) and SPSS version 16 was used for statistical analysis. Results: The highest inhibitory activity (78.85%) was detected at 2.0 mg mL–1. This result indicated that polysaccharide possessed higher inhibitory activity against α-amylase. Conclusion: Hence, the present study showed that mushroom polysaccharides displayed antidiabetic activity. Mushroom polysaccharides are yet to be explored for a lot of various pharmaceuticals for applications in near future.
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How to cite this article:

Periyanan Muni Raj Kumar, Moorthy Saravana Kumar, Arumugam Manivel and Shanmugavadivelu Chandra Mohan, 2018. Structural Characterization and Anti-Diabetic Activity of Polysaccharides from Agaricus bisporus Mushroom. Research Journal of Phytochemistry, 12: 14-20.

DOI: 10.3923/rjphyto.2018.14.20

URL: https://scialert.net/abstract/?doi=rjphyto.2018.14.20

 
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