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Research Journal of Medicinal Plants
  Year: 2011 | Volume: 5 | Issue: 1 | Page No.: 54-64
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Methanol Extract of Three Medicinal Plants from Samburu in Northern Kenya Show Significant Antimycobacterial, Antibacterial and Antifungal Properties

R.M. Mariita, C.K.P.O. Ogol, N.O. Oguge and P.O. Okemo

We determined the antimycobacterial, antibacterial, and antifungal potential of medicinal plants used by the Samburu Community of Northern Kenya, following an ethnobotanical survey. Using BACTEC MGIT 960 system, we assessed plant extract effects on four mycobacterial strains, i.e., Mycobacterium tuberculosis, M. Kansasii, M. fortuitum, and M. smegmatis. For Candida albicans, Salmonella typhi, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumonia, we determined zones of inhibition, Minimum Inhibitory Concentrations (MICs) and minimum bactericidal/fungicidal concentrations (MBCs/MFCs) using standard procedures. Preliminary phytochemistry on the extracts was also carried out using standard procedures. The extracts from Scadoxus multiflorus and Acacia nilotica gave strong antimycobacterial activity (zero GUs) against slow growing mycobacteria strains in all the concentrations tested. Scadoxus multiflorus was also active against M. tuberculosis. Boscia angustifolia was active against M. tuberculosis (183 GUs). Acacia nilotica showed strong antimicrobial activity against E. coli (with of MIC 4.69 mg mL-1 and MBC of 18.75 mg mL-1), P. aeruginosa (with both MIC and MBC of 18.75 mg mL-1), K. pneumoniae, and C. albicans (with MIC of 9.38 mg mL-1 and MBC of 18.75 mg mL-1). Thylachium africanum showed good antimicrobial activity against S. aureus (with MIC of 18.75 mg mL-1 and MBC of 37.5 mg mL-1) and P. aeruginosa (with both MIC and MBC of 4.69 mg mL-1). Preliminary phytochemistry identified six phytochemicals to which tannins was common to all plant extracts. The data suggests that methanolic extracts of at least three plant species could be a rich source of antimicrobial agents. These results provide an indication of merit in their ethnomedicine use by the local communities.
PDF Fulltext XML References Citation Report Citation
  •    Antimicrobial Activity of Plant Secondary Metabolites: A Review
  •    Insecticidal Properties of Pyrethrin Formulations against Immature Stages of Phlebotomine Sand Flies (Diptera: Psychodidae)
  •    A Review on the Recent Advances in Pharmacological Studies on Medicinal Plants; Animal Studies are Done but Clinical Studies Needs Completing
  •    Antimicrobial Activity of the Leaf Extracts of Two Medicinal Plants Against MRSA (Methicilin Resistant Staphylococcus aureus) from Human Urinary Tract Pathogens
  •    Bacteriostatic and Bactericidal Activities of Aspilia mossambicensis, Ocimum gratissimum and Toddalia asiatica Extracts on Selected Pathogenic Bacteria
  •    Anti-microbial Activity of Acacia nilotica Extracts Against Some Bacteria Isolated from Clinical Specimens
  •    Antimicrobial Activity of Saponin Fraction from the Roots of Hemidesmus indicus
  •    Antibacterial Activity of Isolated Constituents and Extract of Roots of Inula racemosa
  •    Comparative Study of the Ethanolic Extracts of Four Nigerian Plants Against Some Pathogenic Microorganisms
  •    Phytochemical and Antibacterial Studies of Root Extract of Cochlospermum tinctorium A. Rich. (Cochlospermaceae)
How to cite this article:

R.M. Mariita, C.K.P.O. Ogol, N.O. Oguge and P.O. Okemo, 2011. Methanol Extract of Three Medicinal Plants from Samburu in Northern Kenya Show Significant Antimycobacterial, Antibacterial and Antifungal Properties. Research Journal of Medicinal Plants, 5: 54-64.


30 April, 2010
Porter P:
Good and useful for my work. came at the right time when am about to collaborate and work on east African ethnomedicine for my pharmaceutical company


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