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Research Journal of Medicinal Plants
  Year: 2008 | Volume: 2 | Issue: 2 | Page No.: 79-85
DOI: 10.3923/rjmp.2008.79.85
 
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Cellular Effects of Garlic (Allium sativum) Extract on Pseudomonas aeruginosa and Staphylococcus aureus
B.E. Boboye and A.J. Alli

Abstract:
Effects of garlic extract at 67, 134 and 201 mg mL-1 on Pseudomonas aeruginosa and Staphylococcus aureus were studied. In the absence of the extract, the cells grew to high densities within 11/2 h at 37 °C. Garlic extract-treated cells reduced in number and died. Percentage living cells at 201 mg mL-1 was 0% for both bacteria. Sucrose and MgSO4 stabilized and protected the cells. At 67, 134 and 201 mg mL-1 of the extract in the presence of this sugar and the compound, 47, 4 and 0% of Ps. aeruginosa cells were viable. Microscopic examination of carbol fuschin and Giemsa stained cells showed that the garlic treated cells were bigger in size than those of untreated ones; and intact and definite nuclei were lacking. The cell wall was the target of attack and the extract was bacteriolytic in action.
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How to cite this article:

B.E. Boboye and A.J. Alli, 2008. Cellular Effects of Garlic (Allium sativum) Extract on Pseudomonas aeruginosa and Staphylococcus aureus. Research Journal of Medicinal Plants, 2: 79-85.

DOI: 10.3923/rjmp.2008.79.85

URL: https://scialert.net/abstract/?doi=rjmp.2008.79.85

 
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