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Research Journal of Environmental Toxicology
  Year: 2015 | Volume: 9 | Issue: 4 | Page No.: 196-203
DOI: 10.3923/rjet.2015.196.203
Fungitoxic Evaluation of New Modified Amidophosphonates (AP1, AP2) on the in vitro Growth of Two Fungal Strains
Amina Saib, Houria Berrebbah, Mohamed-Reda Djebar and Malika Berredjem

Abstract:
We performed this work to highlight the in vitro antifungal properties of two amidophosphonates newly synthesized (AP1, AP2). These molecules were synthesized from amino esters and chloroacetyl chloride in two steps using the Michaelis-Arbuzov reaction. We have selected after testing several concentrations 15, 20 and 25 μM for AP1, 10, 25, 40 μM for AP2. The study of the antifungal power by solid medium-diffusion method was performed after microscopic study and purification of fungal isolates from wheat leaves hard, give us the opportunity to identify two fungi: Septoria tritici and Aalternaria tenuis. Results show an antifungal power of two molecules, the growth inhibition-percentage is higher among Aalternaria tenuis. In addition, AP2 molecule appears to have a stronger antifungal activity. Determining the Minimum Inhibitory Concentration (MIC) by the dilution method in liquid medium, shapeless on the effectiveness of our molecules which is to order of 40 μM (AP1) and 25 μM (AP2) for Septoria tritici, 25 μM (AP1) and 15 μM (AP2) for Alternaria tenuis.
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How to cite this article:

Amina Saib, Houria Berrebbah, Mohamed-Reda Djebar and Malika Berredjem, 2015. Fungitoxic Evaluation of New Modified Amidophosphonates (AP1, AP2) on the in vitro Growth of Two Fungal Strains. Research Journal of Environmental Toxicology, 9: 196-203.

DOI: 10.3923/rjet.2015.196.203

URL: https://scialert.net/abstract/?doi=rjet.2015.196.203

 
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