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Pakistan Journal of Biological Sciences

Year: 2019 | Volume: 22 | Issue: 12 | Page No.: 564-573
DOI: 10.3923/pjbs.2019.564.573

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Authors


Hoda Bakr  Mabrok

Hoda Bakr Mabrok

LiveDNA: 20.29709

Doha Abdou  Mohamed

Doha Abdou Mohamed

LiveDNA: 20.18316

Oksana  Sytar

Oksana Sytar

LiveDNA: 380.10994

Iryna Smetanska

Country: Germany

Keywords


  • oxidative stress markers
  • apple
  • UV light irradiation
  • Anthocyanin
  • cytokines gene expression
Research Article

Biological Evaluation of Golden Delicious Apples Exposure to UV Lights in Rats

Hoda Bakr Mabrok Hoda Bakr  Mabrok's LiveDNA, Doha Abdou Mohamed Doha Abdou  Mohamed's LiveDNA, Oksana Sytar Oksana  Sytar's LiveDNA and Iryna Smetanska
Background and Objective: Anthocyanin is responsible for the red color of apple. Ultraviolet light plays a key role in activating the genes responsible for anthocyanin biosynthesis. However, the most important concern is using UV light irradiation on fruit to increase anthocyanins level and its nutritional quality. In this study, the accumulation of anthocyanin in green apple using UV-B and UV-C was investigated and its biological influence was evaluated in rats. Material and Method: Green Golden delicious apples were irradiated with doses of UV-C and UV-B light for a period of 3 h/day each for 3 days. Two Groups of rats were fed on balanced diet or balanced diet supplemented with 10% apple exposure to UV (AP-UV) for a month. Results: The HPTLC and spectrophotometric determination of anthocyanin revealed that color development was significantly increased by 90% in treated apple compared to the control apples. Histological difference was observed between the 2 groups. Plasma levels of uric acid, the activity of transaminases (ALT and AST) as well as malondialdehyde (MDA) were significantly elevated in AP-UV rats. Plasma total cholesterol, triglycerides and creatinine level did not differ among the 2 groups. Liver MDA and catalase levels were eminent in AP-UV rats compared to control. Gene expression of selected inflammatory cytokines (TNF-α, IL-6 and IL-1β) was significantly up-regulated in liver of AP-UV rats in comparison to control rats. Conclusion: The result revealed that there is a health-hazard linked to feeding rats on diet containing irradiated-apple with UV-B and UV-C, which represented by body weight reduction, inflammation development, liver function and oxidative stress elevation.
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How to cite this article

Hoda Bakr Mabrok, Doha Abdou Mohamed, Oksana Sytar and Iryna Smetanska, 2019. Biological Evaluation of Golden Delicious Apples Exposure to UV Lights in Rats. Pakistan Journal of Biological Sciences, 22: 564-573.

DOI: 10.3923/pjbs.2019.564.573

URL: https://scialert.net/abstract/?doi=pjbs.2019.564.573

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