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Pakistan Journal of Biological Sciences
  Year: 2010 | Volume: 13 | Issue: 18 | Page No.: 866-876
DOI: 10.3923/pjbs.2010.866.876
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A Review on Post-Puberty Hypothyroidism: A Glance at Myxedema
A.R. Mansourian

Hypothyroidism, is a thyroid disorder accompanied by serum thyroid hormone reduction when thyroxin T4, the main thyroid hormone, reduced, it is followed by disruption of a negative-feed back auto regulatory mechanism on pituitary gland and subsequent thyroid stimulating hormone (TSH) which is released into the blood circulation to stimulate the thyroid gland to produce enough thyroid hormone to compensate for the body hormone requirements. Therefore, reduced serum thyroxin(T4) in principle, triidothyronine (T3) and elevated TSH are laboratory indices for the diagnosis of hypothyroidism. At early stage of hypothyroidism although laboratory measurements of thyroid function test are manifest the thyroid disorder but the patient clinical signs and symptoms may remain unnoticed. If the patient undiagnosed and untreated the condition of hypothyroidism worsen and the clinical manifestation begin to show itself and myxedema is a definition given to the whole picture of untreated hypothyroidism at very end stage the patients enter into myxedema comma with eventual death due to the sever symptoms of hypothyroidism. Among important causative factors leading to catastrophic events in myxedema is life threatening hypothermia, heart and cerebral dysfunctions.
PDF Fulltext XML References Citation Report Citation
  •    A Review of Literature on Thyroid Hormone Disorders Originated from Extra Thyroidal Illness
  •    Liver Functional Behavior During Thyrotoxicosis: A Review
  •    Clinical Diagnostic Laboratory Play a Crucial Role in the Management of Thyroid Disorders: A Literature Review
  •    A Review of Literatures on the Adverse Effects of Thyroid Abnormalities and Liver Disorders: An Overview on Liver Dysfunction and Hypothyroidism
  •    The State of Serum Lipids Profiles in Sub-Clinical Hypothyroidism: A Review of the Literature
  •    Thyroid Function Tests During First-trimester of Pregnancy: A Review of Literature
  •    A Survey of Urinary Iodine Concentration in South-east of Caspian Sea in Northern, Iran
  •    Lipid Peroxidation in the Serum of Hypothyroid Patients(In Gorgan-South East of Caspian Sea)
How to cite this article:

A.R. Mansourian , 2010. A Review on Post-Puberty Hypothyroidism: A Glance at Myxedema. Pakistan Journal of Biological Sciences, 13: 866-876.

DOI: 10.3923/pjbs.2010.866.876








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