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Pakistan Journal of Biological Sciences
  Year: 2009 | Volume: 12 | Issue: 10 | Page No.: 804-808
DOI: 10.3923/pjbs.2009.804.808
 
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Hepatitis C Infection and Apoptosis in Hepatocellular Carcinoma

Saad Alkahtani

Abstract:
This study was suggested to show apoptotic markers level in Hepatitis C Carcinoma (HCC) patients related to Hepatitis C Virus (HCV) infection and evaluate the Fas and Fas-L levels in each of non-cancerous individuals (controls), HCC and non-HCC patients to show the apoptosis levels which reflects the progression of inflammation and fibrosis in HCV patients. The collected samples were tested by kinetic, ELISA, RT-PCR and other molecular techniques. The obtained results showed that the Fas-upregulations don’t change in case of positive viral C infection related to HCC and also in non-HCC. But in negative HCV-RNA, Fas-expression in HCC patients is significant. So, the conclusion is neither Fas nor Fas-L may be affected by viral C infection.
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How to cite this article:

Saad Alkahtani , 2009. Hepatitis C Infection and Apoptosis in Hepatocellular Carcinoma. Pakistan Journal of Biological Sciences, 12: 804-808.

DOI: 10.3923/pjbs.2009.804.808

URL: https://scialert.net/abstract/?doi=pjbs.2009.804.808

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