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Pakistan Journal of Biological Sciences
  Year: 2009 | Volume: 12 | Issue: 9 | Page No.: 746-749
DOI: 10.3923/pjbs.2009.746.749
 
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Evaluation of IFN-γ Serum Level in Nephropatic Type 2 Diabetic Patients

Reza Nosratabadi, M.K. Arababadi, G. Hassanshahi, N. Yaghini, V. Pooladvand, Ali Shamsizadeh, E.R. Zarandi and H. Hakimi

Abstract:
The present study was aimed to examine the serum level of IFN-γ in type 2 diabetic patients with nephropatic complications. In this experimental study, serum samples were obtained from 100 type 2 diabetic patients suffering from nephropathy and 100 healthy controls. Serum level of IFN-γ was analyzed by ELISA. Results of this study showed that the mean serum level of IFN-γ was 16.09±2.04 and 4.03±1.00 pg mL-1 in nephropathic patients and healthy controls, respectively. Statistical analysis of data showed that the difference in the IFN-γ serum level was significant between nephropathic patients and controls. Due to the elevated level of IFN-γ in nephropathic patients, it can be possibly concluded that IFN-γ is involved in nephropathy complication of type 2 diabetes.
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How to cite this article:

Reza Nosratabadi, M.K. Arababadi, G. Hassanshahi, N. Yaghini, V. Pooladvand, Ali Shamsizadeh, E.R. Zarandi and H. Hakimi, 2009. Evaluation of IFN-γ Serum Level in Nephropatic Type 2 Diabetic Patients. Pakistan Journal of Biological Sciences, 12: 746-749.

DOI: 10.3923/pjbs.2009.746.749

URL: https://scialert.net/abstract/?doi=pjbs.2009.746.749

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