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Pakistan Journal of Biological Sciences
  Year: 2006 | Volume: 9 | Issue: 2 | Page No.: 299-301
DOI: 10.3923/pjbs.2006.299.301
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The Effect of Halothane on SGOT and SGPT of Operating Room Personnel

Ebrahim Nasiri and Seyed Jalal Hosseinimehr

In this study, liver damage induced by occupational exposure of the anesthetic agent to operating room staff was investigated. A total of 70 persons who employed with more than one year in operation room were investigated. Controls were 70 personnel of the same hospitals with similar conditions who were not working in operation room. Serum levels of alanine aminotransferase (SGPT) and aspartate aminotransferase (SGOT) were measured. Serum SGOT activity was significantly increased in the anesthesiology staff compared to controls. But elevated SGPT in cases was no significant compared to non-exposure group. In this study, although raised aminotransferases enzymes were observed in anesthesiology staff but the serum activity of these enzymes were in the normal range and not observed any abnormality in SGOT and SGPT in staff employed in the operation room. In order to take more care of personnel-health, air concentration of anesthetic gases should be kept as low as possible by help of sufficient room ventilation avoiding unnecessary emissions.
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How to cite this article:

Ebrahim Nasiri and Seyed Jalal Hosseinimehr, 2006. The Effect of Halothane on SGOT and SGPT of Operating Room Personnel. Pakistan Journal of Biological Sciences, 9: 299-301.

DOI: 10.3923/pjbs.2006.299.301






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