
	Pakistan Journal of Biological Sciences
	Year: 2006 \| Volume: 9 \| Issue: 6 \| Page No.: 1139-1142 DOI: 10.3923/pjbs.2006.1139.1142

Toxicity Effect of Zinc Supplementation on the Liver Tissue

M.E Guldur, M. Ozaslan, T. Aytekin, I.H. Kilic and I.D. Afacan

Abstract: The ability of zinc to retard oxidants and to be antioxidant has been recognized for many years. In the present study, it is aimed to determine histological toxic effects of zinc supplementation on hepatic tissue. It was also planned to determine effect of zinc on TAL. In this study, 24 male Wistar albino rats were used. All animals were divided 4 groups; 1 control, 3 experimental group. Three milliliter (227 mg L^-1 day^-1) zinc-sulphate was treated in experimental groups during 15, 30 and 45 days, respectively. TAL, AST and ALT levels from collected cardiac blood samples (3 mL) were measured. For histological investigation, liver tissue was removed and stained with Haematoxilen-eosin. It was determined that, TAL reduced in group I which was given zinc during 15 days and TAL increased in group II and Group III which was given zinc 30 and 45 days, respectively compared to that of group control. Results of the histological investigation showed that no toxicity in even experimental groups.

PDF Fulltext XML References Citation Report Citation

RELATED ARTICLES:

•	In vivo Antitumoral Effect of Diffractaic Acid from Lichen Metabolites on Swiss Albino Mice with Ehrlich Ascites Carcinoma: An Experimental Study

How to cite this article:

M.E Guldur, M. Ozaslan, T. Aytekin, I.H. Kilic and I.D. Afacan, 2006. Toxicity Effect of Zinc Supplementation on the Liver Tissue. Pakistan Journal of Biological Sciences, 9: 1139-1142.

DOI: 10.3923/pjbs.2006.1139.1142

URL: https://scialert.net/abstract/?doi=pjbs.2006.1139.1142

COMMENT ON THIS PAPER

Navigation


		Online First
		Current Issue
		Previous Issues
		Editorial Board
		Submit a Manuscript
		Guide to Authors
		Subscribe to E-alerts

Indexed In


		AGRIS
		ASCI-Database
		Asian Digital Library
		Cambridge Scientific Abstract
		Chemical Abstract Services
		Google Scholar
		ISI Web of Knowledge
		PubMed
		SCIMAGO
		Thomson ISI

Science Alert