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Microbiology Journal

Year: 2011 | Volume: 1 | Issue: 1 | Page No.: 1-7
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Authors

Srikumar Chakravarthi

Nagaraja Haleagrahara

Keywords

Research Article

A Comprehensive Review of the Occurrence and Management of Systemic Candidiasis as an Opportunistic Infection

Srikumar Chakravarthi and Nagaraja Haleagrahara
Candidiasis is a fungal infection which is prone to occur in people with immunosuppression due to debilitating diseases and nosocomial causes. The epidemiology of Candida fungal infections is on the rise and it is a common cause of systemic infections. Even though bloodstream infection in on the decline, the number of risk factors which could eventually lead to candidiasis has been increasing steadily They include immunosuppression due to chemotherapy or corticosteroid therapy, diabetes mellitus, low birth weight in neonates, broad spectrum antibiotics, long term catheterization, haemodialysis and parenteral nutrition. However, it has generally been observed that 3 main groups of patients are associated with candidiasis, namely those with neutropenic cancer, organ or stem cell transplant patients and those undergoing intensive care procedures. Discussion of surveillances and reports will be useful to improve our understanding of the importance of systemic Candida infections and to facilitate the prioritization of the investigation as well as the prevention efforts.
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