
	Journal of Medical Sciences
	Year: 2004 \| Volume: 4 \| Issue: 2 \| Page No.: 170-175 DOI: 10.3923/jms.2004.170.175

Obstructive Sleep Apnea in Elevated Cardiac Output Patients: Hypercapnea-induced Hypoapnea

Al-Said Haffor

Abstract: Obstructive sleep apnea (OSA) relates to cardiovascular diseases. This study evaluated oxygenation and the ventilatory responses to hypercapnea in OSA in whom cardiac output is elevated. Sleep studies were conducted using CASE system. From an arterial line, blood pressure was monitored directly by blood pressure transducer and blood samples were drawn from the same arterial line for arterial blood gases (ABG) analysis. Cardiac output was calculated by the indirect Ficks` method. Gas exchange measures were determined using automatic Douglas Bag System in which expired gases were analyzed online using mass spectrometer (Perkin Elmer-1100). Ventilation was recorded continuously by mass flow meter (TSI). Results of sleep studies indicated that the average obstructive apnea index was 74%. During wake state, the average cardiac output was 9.86 LPM, alveolo-arterial PO₂ differences (A-a PO₂) was 18.82 Torr and normalized VE was 3X for each level of CO₂. At maximum respiratory response PaCO₂ was elevated reflecting increased capacity for CO₂ stores leading to increased CO₂ load on the lungs. Present data indicated that significant obstructive sleep apnea occurs in adult in whom cardiac output, heart rate and blood pressure were elevated during day time. Based on the results of the present study it can be concluded that OSA is considered a risk factor for heart diseases.

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How to cite this article:

Al-Said Haffor , 2004. Obstructive Sleep Apnea in Elevated Cardiac Output Patients: Hypercapnea-induced Hypoapnea. Journal of Medical Sciences, 4: 170-175.

DOI: 10.3923/jms.2004.170.175

URL: https://scialert.net/abstract/?doi=jms.2004.170.175

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