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Journal of Medical Sciences
  Year: 2004 | Volume: 4 | Issue: 2 | Page No.: 170-175
DOI: 10.3923/jms.2004.170.175
 
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Obstructive Sleep Apnea in Elevated Cardiac Output Patients: Hypercapnea-induced Hypoapnea

Al-Said Haffor

Abstract:
Obstructive sleep apnea (OSA) relates to cardiovascular diseases. This study evaluated oxygenation and the ventilatory responses to hypercapnea in OSA in whom cardiac output is elevated. Sleep studies were conducted using CASE system. From an arterial line, blood pressure was monitored directly by blood pressure transducer and blood samples were drawn from the same arterial line for arterial blood gases (ABG) analysis. Cardiac output was calculated by the indirect Ficks` method. Gas exchange measures were determined using automatic Douglas Bag System in which expired gases were analyzed online using mass spectrometer (Perkin Elmer-1100). Ventilation was recorded continuously by mass flow meter (TSI). Results of sleep  studies  indicated that the average   obstructive apnea index  was  74%. During wake state, the average cardiac output was 9.86 LPM, alveolo-arterial PO2 differences (A-a PO2) was 18.82 Torr and normalized VE was 3X for each level of CO2. At maximum respiratory response PaCO2 was elevated reflecting increased capacity for CO2 stores leading to increased CO2 load on the lungs. Present data indicated that significant obstructive sleep apnea occurs in adult in whom cardiac output, heart rate and blood pressure were elevated during day time. Based on the results of the present study it can be concluded that OSA is considered a risk factor for heart diseases.
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How to cite this article:

Al-Said Haffor , 2004. Obstructive Sleep Apnea in Elevated Cardiac Output Patients: Hypercapnea-induced Hypoapnea. Journal of Medical Sciences, 4: 170-175.

DOI: 10.3923/jms.2004.170.175

URL: https://scialert.net/abstract/?doi=jms.2004.170.175

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