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International Journal of Pharmacology
  Year: 2006 | Volume: 2 | Issue: 4 | Page No.: 435-438
DOI: 10.3923/ijp.2006.435.438
 
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Anti-inflammatory, Analgesic and Antipyretic Activities of Dicliptera verticillata

Wamtinga Richard Sawadogo , Rainatou Boly , Marius Lompo , Noya Some , Charles Euloge Lamien , Innocent Pierre Guissou and Odile Germaine Nacoulma

Abstract:
The methanol extract of Dicliptera verticillata stems with leaves was investigated for its anti-inflammatory, analgesic and antipyretic activities in animal models. The extract was found to reduce significantly (p<0.001) the formation of oedema induced by carrageenan after 3 h. In the acetic acid induced writhing model, the extract has shown a good analgesic effect characterised by a significant reduction (p<0.001) in the number of writhes with all the doses used when compared to the control untreated group. In the antipyretic assay, the extract was efficient on yeast-induced hyperpyrexia in mice, mainly 2 h after drugs administration. The results give a scientific basis to the traditional uses of Dicliptera verticillata, mainly those involving pain, fever and inflammation.
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How to cite this article:

Wamtinga Richard Sawadogo , Rainatou Boly , Marius Lompo , Noya Some , Charles Euloge Lamien , Innocent Pierre Guissou and Odile Germaine Nacoulma , 2006. Anti-inflammatory, Analgesic and Antipyretic Activities of Dicliptera verticillata . International Journal of Pharmacology, 2: 435-438.

DOI: 10.3923/ijp.2006.435.438

URL: https://scialert.net/abstract/?doi=ijp.2006.435.438

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