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International Journal of Pharmacology

Year: 2006 | Volume: 2 | Issue: 4 | Page No.: 435-438
Research Article

Anti-inflammatory, Analgesic and Antipyretic Activities of Dicliptera verticillata

Wamtinga Richard Sawadogo
Institute of Research in Health Sciences, University of Ouagadougou
Rainatou Boly
Institute of Research in Health Sciences, University of Ouagadougou
Marius Lompo
Institute of Research in Health Sciences, University of Ouagadougou
Noya Some
Health Sciences Research Institute, University of Ouagadougou
Charles Euloge Lamien
Institute of Research in Health Sciences, University of Ouagadougou
Innocent Pierre Guissou
Department of Applied Pharmaceutical Sciences/Pharmacology -toxicology/University of Ouagadougou
Odile Germaine Nacoulma
Institute of Research in Health Sciences, University of Ouagadougou
The methanol extract of Dicliptera verticillata stems with leaves was investigated for its anti-inflammatory, analgesic and antipyretic activities in animal models. The extract was found to reduce significantly (p<0.001) the formation of oedema induced by carrageenan after 3 h. In the acetic acid induced writhing model, the extract has shown a good analgesic effect characterised by a significant reduction (p<0.001) in the number of writhes with all the doses used when compared to the control untreated group. In the antipyretic assay, the extract was efficient on yeast-induced hyperpyrexia in mice, mainly 2 h after drugs administration. The results give a scientific basis to the traditional uses of Dicliptera verticillata, mainly those involving pain, fever and inflammation.
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How to cite this article

Wamtinga Richard Sawadogo, Rainatou Boly, Marius Lompo, Noya Some, Charles Euloge Lamien, Innocent Pierre Guissou and Odile Germaine Nacoulma, 2006. Anti-inflammatory, Analgesic and Antipyretic Activities of Dicliptera verticillata . International Journal of Pharmacology, 2: 435-438.

DOI: 10.3923/ijp.2006.435.438

URL: https://scialert.net/abstract/?doi=ijp.2006.435.438

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