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International Journal of Biological Chemistry
  Year: 2009 | Volume: 3 | Issue: 4 | Page No.: 148-152
DOI: 10.3923/ijbc.2009.148.152
 
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Natural Cumin Seeds for Wound Healing Activity in Albino Rats
D.N. Patil, A.R. Kulkarni, A.A. Shahapurkar and B.C. Hatappakki

Abstract: To screen the wound healing activity of extract and different fractions of cumin seeds on excision, incision, granuloma wound models in albino rats. The cumin seeds obtained from the plant known as Cuminum cyminum were subjected to solvent extraction with 90% ethanol, its successive fractionation by petroleum ether (40-60°) and ethyl acetate. Extract and fractions were screened for wound healing properties on excision, incision and granuloma wound models in albino rats. The exactly weighed quantity of (250 mg kg-1 b.wt.) alcoholic extract and its petroleum ether fraction showed better epithelisation (p<0.001) as compared to control in resutured incision and granuloma wound models. It is concluded that, alcoholic extract and its petroleum ether fraction of seeds of cumin showed promoted wound healing activity on excision, incision and granuloma wound models. However, ethyl acetate fraction failed to show significant wound healing activity.
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How to cite this article:

D.N. Patil, A.R. Kulkarni, A.A. Shahapurkar and B.C. Hatappakki, 2009. Natural Cumin Seeds for Wound Healing Activity in Albino Rats. International Journal of Biological Chemistry, 3: 148-152.

DOI: 10.3923/ijbc.2009.148.152

URL: https://scialert.net/abstract/?doi=ijbc.2009.148.152
 
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