Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Biotechnology
  Year: 2015 | Volume: 14 | Issue: 3 | Page No.: 109-118
DOI: 10.3923/biotech.2015.109.118
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail
Effect of DksA Protein on the Susceptibility of Escherichia coli Towards Novel Amine N-Halamine Polymeric Nanoparticles as Powerful Antibiotics
Qigeqi Dong, Lifei Fan, Alideertu Dong and Morigen

Abstract:
A novel amine N-halamine polymeric nanoparticles (ANHP NPs) based on 4-(allyloxy)-2,2,6,6-tetramethylpiperidine (ATMP) were well developed as an antimicrobial agents by the aid of the radical copolymerization for deactivating pathogenic bacteria. The as-prepared ANHP NPs were systematically characterized by the different physical and chemical techniques like 1H NMR, FTIR, SEM and the modified iodometric/thiosulfate method. Sterilizing action of the ANHP NPs on bacterial strain was evaluated by selecting different types of Escherichia coli (E. coli) strains as model microorganisms. The effect of DksA protein on the susceptibility of E. coli towards the ANHP NPs was investigated via the plate counting technique and the zone of inhibition test. The experimental results showed that DksA protein has an excellent resistance against the ANHP NPs. Such an in-depth study on the DksA effect on the susceptibility of E. coli against the antibiotics opens up a new thought for us to develop the novel potential antibiotics.
PDF Fulltext XML References Citation Report Citation
How to cite this article:

Qigeqi Dong, Lifei Fan, Alideertu Dong and Morigen , 2015. Effect of DksA Protein on the Susceptibility of Escherichia coli Towards Novel Amine N-Halamine Polymeric Nanoparticles as Powerful Antibiotics. Biotechnology, 14: 109-118.

DOI: 10.3923/biotech.2015.109.118

URL: https://scialert.net/abstract/?doi=biotech.2015.109.118

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

       

       

Curve Bottom