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Biotechnology
  Year: 2008 | Volume: 7 | Issue: 4 | Page No.: 787-792
DOI: 10.3923/biotech.2008.787.792
 
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Variant Molecular Marker in MHC Effect Fertility Trait in Sheep
M.R. Mir and H. Geldermann

Abstract:
Present study was aimed at comparative analysis of microsatellite polymorphism at DRB1 intron 2 locus of Ovine MHC in German Merino sheep. Experiment was conducted in four consecutive lambings comprising flock of adult males, females and offspring`s totaling 639 individuals. A total of 16 DRB1 microsatellite alleles, ranging between 353-857 bp were detected associated with variable reproductive performances among males and females. Ewes carrying allele 386 bp had a higher (p<0.01) number of lambs born, carriers of allele 389 bp had a lower (p<0.01) number of lambs weaned and allele 411 bp occurred together with higher values of all recorded fertility traits. The associations of different alleles with variable reproductive traits in sheep could be individual variability to humoral immune response, cell recognition or tissue differentiation between carriers of various MHC genotypes. The observed associations within DRB1 intron 2 locus of Ovine MHC in German Merino sheep may be used as a molecular marker for identifying QTL in genetic improvement of the sheep.
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How to cite this article:

M.R. Mir and H. Geldermann, 2008. Variant Molecular Marker in MHC Effect Fertility Trait in Sheep. Biotechnology, 7: 787-792.

DOI: 10.3923/biotech.2008.787.792

URL: https://scialert.net/abstract/?doi=biotech.2008.787.792

 
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