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Asian Journal of Animal and Veterinary Advances
  Year: 2014 | Volume: 9 | Issue: 4 | Page No.: 253-261
DOI: 10.3923/ajava.2014.253.261
 
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Polymorphism of FUT1 Gene M307 and its Relationship with Partial Immune Indexes and Economic Traits in Yorkshire Pigs

Shiping Zhu, Ying Liu, Wenhua Dong, Xianrui Zheng, Guoqiang Zhu, Shenglong Wu and Wenbin Bao

Abstract:
To assess the feasibility of FUT1 gene M307 as a disease resistance genetic marker in Yorkshire pigs, this experiment adopted PCR-RFLP method to investigate the genetic variations at M307 of FUT1 gene in purebred Yorkshire (total 218 individuals), determined partial biochemical parameters and important cytokines using the automatic blood cell analyzer and ProCarta immunoassay kits and assayed a number of economic traits including eye muscle thickness, backfat thickness, growth rate and reproductive performance. This study also analyzed the relationship between polymorphism of FUT1 gene M307 and partial immune indexes, vital economic traits. The results showed that there were three genotypes (AA, AG and GG) in Yorkshire test groups, in which the allele G was dominant one. FUT1 gene M307 deviated from Hardy-Weinberg equilibrium (p<0.01) in the population. Correlation analysis showed that the level of thrombocytocrit (PCT) in AG, GG genotype individuals were significantly higher than that in AA genotype individuals (p<0.05), while there were no significant difference between AG and GG genotypes (p>0.05). The individuals with GG genotype were significantly higher than those with AG genotype (p<0.01) in IFN-γ, TGF-β and TNF-α. In terms of the age at 100 kg, individuals with AA type were significantly higher than those with AG type (p<0.05), the average age at 100 kg of AA type individuals was 4.23 days less than GG type individuals. From the 3rd-5th parity, the Total Number Born (TNB) and Number Born Alive (NBA) demonstrated a trend of AA>AG>GG, individuals with AA type were significantly higher than those individuals with GG type (p<0.05) in TNB and NBA at 3rd and 5th parities. These results indicated that AA genotype, as an ETEC F18 resistance genetype, would also improve growth rate and reproduction performance of Yorkshire pigs, but reduce their general disease resistance ability.
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How to cite this article:

Shiping Zhu, Ying Liu, Wenhua Dong, Xianrui Zheng, Guoqiang Zhu, Shenglong Wu and Wenbin Bao, 2014. Polymorphism of FUT1 Gene M307 and its Relationship with Partial Immune Indexes and Economic Traits in Yorkshire Pigs. Asian Journal of Animal and Veterinary Advances, 9: 253-261.

DOI: 10.3923/ajava.2014.253.261

URL: https://scialert.net/abstract/?doi=ajava.2014.253.261

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