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Asian Journal of Animal and Veterinary Advances

Year: 2011 | Volume: 6 | Issue: 1 | Page No.: 96-100
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Authors

Y.S. Karafakioglu

I.H. Cigerci

A.F. Fidan

Keywords

Research Article

The Effects of Taurine on Aminolevulinic Acid Dehydratase Activity in Nonylphenol-Induced Toxicity

Y.S. Karafakioglu, I.H. Cigerci and A.F. Fidan
The aim of this study was to investigate the effects of taurine on blood aminolevulinic acid dehydratase (ALAD) activity in nonylphenol-induced rats. Forty rats were divided into 5 groups each containing 8 Wistar-albino male rats: control group (C) by standard rat feed, taurine group (T) by standard rat feed + 3% taurine (v/w) in drinking water, nonlyphenol group (NP) by standard rat feed + 50 μg kg-1 diet Nonlyphenol, Nonlyphenol + Taurine group (NPT) by standard rat feed + 50 μg kg-1 diet Nonlyphenol + 3% taurine (v/w) in drinking water and alcohol group (A) by standard rat feed +50 μL kg-1 diet alcohol were fed ad libitum for 30 days during the study. The blood ALAD activity significantly increased in T group compared the other experimental groups. Nonlyphenol treatment significantly decreased the blood ALAD activity as compared to control. Decreased levels of blood ALAD activity in NP group were significantly increased in NPT group. The ALAD activity significantly decreased in A group compared the T groups. The results demonstrate that taurine could provide great advantages against to side effects of nonlyphenol toxication on ALAD activity in rats those exposed to Nonylphenol.
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