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Asian Journal of Animal and Veterinary Advances
  Year: 2011 | Volume: 6 | Issue: 12 | Page No.: 1204-1213
DOI: 10.3923/ajava.2011.1204.1213
 
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A Retrospective Analysis on Phylogeny and Evolution of CPV Isolates in China
Shuizhong Han, Baozhu Qi and Xiaoying Zhang

Abstract:
Canine parvovirus (CPV) is a widespread pathogen among canine in China. It has made great veterinary public health burden and economic loss. Three CPV-2 variations, CPV-2a, CPV-2b and CPV-2c, have emerged, however, the CPV-2 variations distribution and the dominant epidemic strain in China are still undetermined. To better understand the epidemiology of CPV in China, the CPV-VP2 gene sequences which had been submitted to GenBank from 1983 to 2011 in China were analyzed and were compared with the representative references from other countries. Phylogenetic trees based on the VP2 sequences were constructed and they showed that the Chinese CPV-2a and CPV-2b strains were close to the Korean and Vietnam strains respectively. It was found that CPV-2a had been the prevalent strain in China and most CPV isolates existed in northeast China. The VP2 protein in CPV-2a and CPV-2b isolated from China had three mutations compared to the American standard strain: 297Ser-Ala, 324Tyr-Ile and 555Ile-Val.
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How to cite this article:

Shuizhong Han, Baozhu Qi and Xiaoying Zhang, 2011. A Retrospective Analysis on Phylogeny and Evolution of CPV Isolates in China. Asian Journal of Animal and Veterinary Advances, 6: 1204-1213.

DOI: 10.3923/ajava.2011.1204.1213

URL: https://scialert.net/abstract/?doi=ajava.2011.1204.1213

 
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