M. Helal Uddin Biswas
Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh
A. R. M. Ruhul Amin
Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh
M. Shah Alam Bhuiyan
Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh
M. A. Rashid
Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh
M. Ahmed
Department of Pharmacy, University of Dhaka, Dhaka1000, Bangladesh
M. A. Islam
Open School, Bangladesh Open University,
Gazipur-1 704, Bangladesh
ABSTRACT
A Monocillium species isolated from a soil sample which grown optimally in Czapek`s dox broth (acidic) medium yielded the metabolic compound HB identified as a mixture of novel compounds, Monocillinols A and B. Antibacterial activities of the compound were observed against fifteen Gram positive and Gram negative pathogenic organisms. The compound showed significant antibacterial activities against all pathogenic organisms tested except Gram negative Shigella sonnei. The minimum inhibitory concentration (MIC) values of the compound were determined against Bacillus subtilis, Sarcina lutea, Staphylococcus aureus, Shigella dysenteriae, Escherichia coli and Salmonella typhi and found to be 128, 256, 128, 128, 128 and 128 g/ml, respectively.
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How to cite this article
M. Helal Uddin Biswas, A. R. M. Ruhul Amin, M. Shah Alam Bhuiyan, M. A. Rashid, M. Ahmed and M. A. Islam, 2001. In vitro Antibacterial Screening of the Metabolite of a Monocillium Species Isolated from a Soil Sample of Bangladesh. Journal of Medical Sciences, 1: 25-27.
DOI: 10.3923/jms.2001.25.27
URL: https://scialert.net/abstract/?doi=jms.2001.25.27
DOI: 10.3923/jms.2001.25.27
URL: https://scialert.net/abstract/?doi=jms.2001.25.27
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