
	Research Journal of Medicinal Plants
	Year: 2016 \| Volume: 10 \| Issue: 1 \| Page No.: 98-105 DOI: 10.3923/rjmp.2016.98.105

Protective Role of Aqueous Guava Leaf Extract Against Caffeine Induced Spermatotoxicity in Albino Rats

U.B. Ekaluo, E.V. Ikpeme, U.U. Uno, S.O. Umeh

and F.A. Erem

Abstract: This study investigated the protecting potential of Aqueous Guava (Psidium guajava) Leaf Extract (AGLE) against caffeine induced spermatotoxicity in albino rat models. Thirty healthy and sexually matured albino rats were divided into five groups of six rats each using a completely randomized design. They were treated with caffeine and AGLE combinations orally for 65 days. The result showed that caffeine significantly (p<0.05) reduced sperm viability, sperm count and sperm motility, while sperm head abnormality increased in caffeine treated rats when compared to the control. However, AGLE significantly (p<0.05) protected the treated albino rat models from caffeine induced spermatotoxicity in a dose-dependent manner. These results show that AGLE is effective in protecting albino rat models against caffeine induced spermatotoxicity in a dose dependent manner.

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How to cite this article:

U.B. Ekaluo, E.V. Ikpeme, U.U. Uno, S.O. Umeh and F.A. Erem, 2016. Protective Role of Aqueous Guava Leaf Extract Against Caffeine Induced Spermatotoxicity in Albino Rats. Research Journal of Medicinal Plants, 10: 98-105.

DOI: 10.3923/rjmp.2016.98.105

URL: https://scialert.net/abstract/?doi=rjmp.2016.98.105

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