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Research Journal of Medicinal Plants

Year: 2007 | Volume: 1 | Issue: 3 | Page No.: 100-105
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Authors

A. Umamaheswari

Nivedita Govindan

Keywords

Research Article

Anticancerous Effect of Hibiscus sabdariffa Leaves on Hepatocellular Carcinoma Cell Line Hep 3B

A. Umamaheswari and Nivedita Govindan
Hibiscus sabdariffa L. (Malvaceae) is a natural plant containing a lot of pigments that was found to possess anti-oxidant activity. Therefore, the present study was aimed to evaluate the anticancer potential of Hibiscus sabdariffa (H. sabdariffa) leaves on Hep 3B. Different extracts of methanol, ethanol, ethyl acetate and chloroform were prepared and tested for their cytotoxic effect by MTT assay in a dose and time dependent manner. Among the different organic solvent extracts tested, methanolic extract showed a greater cytotoxic effect (i.e.,) IC 50 value of 50% reduction when compared to others. The time required to show 75% decrease in cell number was found to be 24 h.
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How to cite this article

A. Umamaheswari and Nivedita Govindan, 2007. Anticancerous Effect of Hibiscus sabdariffa Leaves on Hepatocellular Carcinoma Cell Line Hep 3B . Research Journal of Medicinal Plants, 1: 100-105.

URL: https://scialert.net/abstract/?doi=rjmp.2007.100.105

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