Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Asian Journal of Biological Sciences
  Year: 2013 | Volume: 6 | Issue: 4 | Page No.: 234-238
DOI: 10.3923/ajbs.2013.234.238
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail
Protective Effect of Erythrina senegalensis (DC) Leaf Extract on Carbon Tetrachloride-induced Liver Injury in Rats
H.Y. Wakawa and M. Hauwa

Abstract:
The aqueous leaf extract of Erythrina senegalensis (ES) was evaluated for its protective activity against carbon tetrachloride (CCl4)-induced liver injury. A 100, 200 and 400 mg kg-1 b.wt. of the ES leaf extract was administered to different groups of rats for 7 days prior to the CCl4 administration. A significant (p<0.05) decrease was observed in both the groups pretreated with 200 and 400 mg kg-1 b.wt. of the leaf extract on the levels of the enzymes and non enzyme markers of tissue damage, lipid peroxidation and relative organ weights and this is shown to be dose dependant when compared to rats that were given CCl4 only. These results showed that ES possess hepatoprotective principle (s) that was (were) able to prevent the toxicity of CCl4 against the liver of rats.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Ziziphus mauritiana Fruit Extract Inhibits Carbon Tetrachloride-induced Hepatotoxicity in Male Rats
How to cite this article:

H.Y. Wakawa and M. Hauwa, 2013. Protective Effect of Erythrina senegalensis (DC) Leaf Extract on Carbon Tetrachloride-induced Liver Injury in Rats. Asian Journal of Biological Sciences, 6: 234-238.

DOI: 10.3923/ajbs.2013.234.238

URL: https://scialert.net/abstract/?doi=ajbs.2013.234.238

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 

       

       

Curve Bottom