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Asian Journal of Biological Sciences

Year: 2010 | Volume: 3 | Issue: 1 | Page No.: 28-33
Research Article

Effect of Gymnema Leaf Extract on UV-Induced Damage on Salmonella typhi

P.R. Rachh
Pharmacy College, Metoda, Rajkot, Gujarat, India
M.R. Rachh
K.B. Institute of Pharmaceutical Education and Research, Gandhinagar, Gujarat, India
M.M. Soniwala
L.J. Institute of Pharmacy and Research Centre, Ahmedabad, Gujarat, India
V.D. Joshi
Pharmacy College, Metoda, Rajkot, Gujarat, India
A.P. Suthar
Pharmacy College, Metoda, Rajkot, Gujarat, India
Ultra Violet (UV) radiation is capable of producing oxygen induced damage in bacteria. Standardization of Salmonell typhi bacteria strain was done and the free radical scavengering effect of gymnema leaf extract was determined on UV light induced free radicals. Total flavonoid, total phenolic and total tannin content of gymnema leaf extract was also determined. Extract of gymnema leaf significantly inhibited UV induced damage in Salmonella typhimurium. In gymnema leaf extract total flavonoid was found to be 0.2574 mg g-1 expressed as rutin, total phenolic was found to be 15.16 mg g-1 expressed as gallic acid and total tannin content was found to be 2.0785% expressed as tannic acid. The protection of Salmonell typhi may be due to the presence of acidic compounds, flavonoids, saponins, tannins (phenolic compounds) and triterpenoids found in the preliminary photochemical screening.
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How to cite this article

P.R. Rachh, M.R. Rachh, M.M. Soniwala, V.D. Joshi and A.P. Suthar, 2010. Effect of Gymnema Leaf Extract on UV-Induced Damage on Salmonella typhi. Asian Journal of Biological Sciences, 3: 28-33.

URL: https://scialert.net/abstract/?doi=ajbs.2010.28.33

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