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Articles by M.A. Asad
Total Records ( 3 ) for M.A. Asad
  M.E. Ali , M.A. Salam , M.A. Asad , M. Saifuzzaman and M.M. Sarder
  In this study, 5 weeks old mice weighing 22±2 g were grouped in four, each group consisting of six animals. Group-I, II, III and IV of the animals were fed by a standard diet quantity sufficient, normal diet with dissolved arsenic, arsenic with folic acid mixed and arsenic with vitamin C mixed, respectively. Blood was collected from the sacrificed animals and the blood glucose levels were determined by spectrophotometrically and glucometer. The average blood glucose level of arsenic induced animals was 9.37 mmol L-1 compared to 6.53 mmol L-1 in control animals whereas the blood glucose level of Group-III and Group-IV were 6.73 and 7.03 mmol L-1, respectively. Weight gain of the arsenic induced animals was lower compared to that of the animals fed with normal diet, folic acid mixed diet or vitamin C mixed diet. After sacrifice, the weight of kidney, heart and lung of arsenic induced animals were less than that of the Group-III and Group-IV. The reduction of arsenic induced higher blood glucose level by folic acid and vitamin C demonstrates that folic acid and vitamin C has significant effect in preventing arsenic induced disease.
  M.E. Ali , M.A. Salam , M.A. Asad and M. Saifuzzaman
  Ketoprofen, a widely used analgesic drug is available in two solid dosage forms in the pharma-market of Bangladesh: enteric-coated tablet and capsule of sustained-release pattern. Seven brands of ketoprofen enteric-coated tablets and four brands of ketoprofen sustained release capsules were studied for their in vitro release behavior as well as potency status. From the seven samples of tablets, two brands (KT-03 and KT-07) were found noncompliant in respect of disintegration test in acid stage, whereas all the brands complied with BP (British Pharmacopoeia) specification in buffer stage at pH 6.8. The dissolution study of ketoprofen tablets were carried out in both acid and buffer stages and all the samples satisfied with USP specification in both stages. All of the brands of ketoprofen capsule also complied with the USP specification. Potency was determined by UV spectroscopic method according to BP. Two brands (KT-03 and KT-07) of tablets were found non-compliant, whereas all the brands of capsules exerted compliance in respect of potency.
  M.A. Salam , M.S. Hossain , M.E. Ali , M.A. Asad and M.H. Ali
  The experiment was carried out to determine the presence and numbers of arsenic resistant bacteria population. In this study, soil samples were collected from different contaminated sites of Khulna shipyard, Rupsha, Baghmara and Ramnagor in Khulna district of Bangladesh. Twenty arsenic resistant bacterial strains were isolated from the soil samples. They were isolated by growing them on Nutrient Broth (NB) medium impregnated with high concentration of arsenic. From them, six strains Bacillus lichnefomis (1/10), Listeria murrayi (2/9), Bacillus polymyxa (3/6), Moraxella urethralis (4/9) and Planococcus citreus (5/8) and Pseudomonas fluorescens (6/8) were finally selected and studied their morphological and biochemical characters in details. All six strains were able to tolerate very high concentration (>100 ppm). The optimum pH and temperature for the growth of all six strains were 8.5 and 37°C, respectively. It was concluded that bacteria living in arsenic free environment must posses a mechanism necessary to resist other toxic levels of arsenic.
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