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Articles by Yi Tang
Total Records ( 2 ) for Yi Tang
  Yi Tang , Huanxiu Li , Zesheng Yan , Jia Lai , Qian Luo and Li Zhang
  The effects of growth regulators, Thidiazuron (TDZ), silver nitrate (AgNO3), triacontanol and glutaminate on adventitious buds induction from anther culture of bitter melon (Momordica charantia L.) were investigated. It was found that triacontanol was advantageous for buds development and adventitious buds differentiated from anther culture of bitter melon first time. On medium supplemented with glutaminate 0.1 mg L-1, protuberant structures differentiated on the surface of callus. AgNO3 and TDZ has no significant effect on promoting adventitious buds formation from anther culture of bitter melon.
  Yi Tang , Zhongyu Liu , Ling Zhao , Thomas L. Clemens and Xu Cao
  β-Catenin functions both as an adherens junction adhesion protein and as an essential mediator of the canonical Wnt signaling pathway. Wnts stabilize β-catenin and promote its accumulation in the nucleus, where it regulates transcription of the target genes. Here we show that Smad7 promotes cell-cell adhesion by stabilizing β-catenin and consequently increases the β-catenin-E-cadherin complex level at the plasma membrane. A Smad7-Axin interaction disassociates GSK-3β and β-catenin from Axin, as well as inhibits the recruitment of Smurf2, an E3 ligase, to β-catenin, thus protecting β-catenin from phosphorylation and degradation. Smad7 increases the stabilized β-catenin to form a complex with E-cadherin and stabilizes the E-cadherin-β-catenin complex. Thereby, rather than being translocated to the nucleus for regulating the target gene transcription, Smad7-stabilized-β-catenin is shunted to the E-cadherin complex to modulate cell-cell adhesion.
 
 
 
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