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Articles by Y. Norimah
Total Records ( 4 ) for Y. Norimah
  A.B.Z. Zuki , A. Fadilah , M. Zamri-Saad , M.Y. Loqman , Y. Norimah and H. Asnah
  The present study was designed to evaluate and compare the natural coral and Calcium Phosphate Cement (CPC) post-implantation in sheep femoral bone. Twenty one adult, male sheep (weight 15-20 kg) were used in this study and were divided into two groups. Group one consists of 12 animals and implanted with natural coral while group two consists of 9 animals and implanted with CPC material. The large cortical defect (2.5x0.5x0.5 cm) was created surgically on the left proximal femur and replaced by the implant. Radiographs and ultrasonographs were obtained immediately after surgery and at 2, 4, 8 and 12 weeks post-implantation. Both ultrasonographs and radiographs taken at 8 and 12 weeks showed that the implants had been resorbed and left the space that much reduced in size. There was no sign of implant rejection observed in all animals. The sheep were euthanased at 2, 4, 8 and 12 weeks post-implantation and the bone examined grossly. Samples of the implant were taken for histological examination. Microscopically, natural coral exhibited rapid resorption and progressively replaced by new bone. At 8 weeks post-implantation, there was no more coral implant present and by week 12 the implant site was almost completely closed and filled by mature bone. Meanwhile, CPC implant was clearly seen and demonstrated only marginal bone formation at the end of 12 weeks study. The coral implant exhibited good bone substitute, but it has fast resorption rate. Thus, it may suitable for less compact bone with small defect.
  A.J. Awang-Hazmi , A.B.Z. Zuki , M.M. Noordin , A. Jalila and Y. Norimah
  The study was conducted to determine the composition of mineral content of cockle (Anadara granosa) shells from 3 major cockle cultivation of West Coast of Malaysia. Three samples of cockle shells from three different sources were evaluated to determine the content of 12 macro-and micro-elements (Calcium (Ca), Carbon (C), Magnesium (Mg), Sodium (Na), Phosphorus (P), Potassium (K), Ferum (Fe), Copper (Cu), Nickel ( Ni), Zink (Zn), Boron and Silica (Si)). For convenience and ease of reference, Ca and C were combine into one unit (Calcium Carbonate, CaC) while Mg, Na, P and K was evaluated individually and Fe, Cu, Ni, Zn, B and Si were evaluated as one group (others). Analysis of elements content was done using inductively Coupled plasma, Auto Analyzer, an Atomic Absorption Spectrophotometer and Carbon Analyzer. Results in this study revealed that the mineral compositions of cockle shells from 3 different sources in West Coast of Peninsular Malaysia were consistence almost in all the samples. The percentage of CaC comprises of more than 98.7% of the total minerals content of the cockle shells of the 3 sources. About 1.3 % of the composition are comprises of Mg, Na, P, K and others (Fe, Cu, Ni, B, Zn and Si).Overall, the minerals composition of cockle shells of West Coast of Peninsular Malaysia are as followed: CaC 98.7 %, Mg 0.05%, Na 0.9%, p 0.02 and others 0.2%.
  A.B.Z. Zuki , D. Saudi , A. Jalila , R. Mustaffa and Y. Norimah
  The present study was conducted to evaluate the potential of cockle (Anadara granosa) shell as an alternative biomaterial for bone substitute. The cockle shells were cleaned thoroughly and dried in oven (50 C) for 3 days. The shells were then ground by using Blendor (240V) and sieved twice at 850 m and followed by 420 m. The powder was compressed to form dense pellet by using uniaxial compress technique. Three adult New Zealand White rabbits were used in this study. Each rabbit was implanted with cockle shell, cockle shell+binder and cockle shell+Hydroxiappatite (HA). The right and left gluteal muscles was implanted with cockle shell+binder and cockle shell+HA respectively, while the semitendinosus muscle was implanted with cockle shell. Radiography and ultrasonography techniques were used to evaluate the implant materials post-implantation. The animals were euthanased at three weeks post-implantation and samples of the implant materials and surrounding tissues were taken for histological evaluation. Result of the study revealed that after three weeks post-implantation, no new bone formation was detected. However, the ultrasound and the radiographic evaluations revealed the absorption and tissue reaction at the implantation sites.
  M.Z. Rozaini , A.B.Z. Zuki , M.M. Noordin , Y. Norimah and A. Nazrul Hakim
  The study was conducted to evaluate the macroscopic changes of burn wounds healing progress as a response to various types of honey applied topically. A total of 42 male, Sprague Dawley rats (weight 200-300 g) were used in this study. The animals were randomly divided into seven experimental groups consisted of 6 animals for each group. Macroscopic changes of the burn wounds healing progress were evaluated at day 0 post burned and subsequently at days 3, 7, 14, 21 and 28 post burned. To determine the rate of wound contraction the changes in the size of burn wounds were traced by measuring the diameter of the wound area both longitudinally and transversely across the body length using a ruler. The change in wound diameter at various time intervals was calculated as the percentage of wound area that had healed. The results obtained from this study indicated that topical application of Manuka and Melaleuca (Gelam) honeys significantly stimulated the rate of burn wound healing as assessed by increased in the rate of wound contraction and from the observation of gross appearances.
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