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Articles by Rashmi Arora
Total Records ( 3 ) for Rashmi Arora
  N.S. Gill , Nistha Marwah , Rashmi Arora and M. Bali
  The present study was to investigate antioxidant, analgesic and antiulcer effect of ethanolic seeds extract of Trichosanthes cucumerina. Extraction was done by cold maceration method for 72 h using ethanol as solvent. The preliminary phytochemical screening showed the presence of triterpenoids, flavanoids and sterols. The antioxidant activity was determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging method. The extract showed maximum scavenging activity 86.2% at 150 μg mL-1 by DPPH method as compared to standard antioxidant ascorbic acid. Further extract was studied for antiulcer activity by ethanol induced ulcer model and Non steroidal anti-inflammatory drugs induced method and analgesic activity by Eddy’s hot plate method. Ethanolic extract of Trichosanthes cucumerina cause 72.1 and 57.1% inhibition of ulcer in Non steroidal anti-inflammatory drugs induced model and ethanol induced model at 500 mg kg-1. Result concluded that Ethanolic extract of Trichosanthes cucumerina possess high antiulcer activity which is due to high antioxidant activity and extract also showed potential analgesic activity by Eddy’s hot plate method.
  Rashmi Arora , Naresh Singh Gill , Sukhwinder Kaur and Ajay Deep Jain
  Abrus precatorius Linn. is a leguminous plant of the fabaceae family whose stem, bark, leave and roots are widely used for medicinal purposes in tropical and subtropical regions of the world. The plant parts are purgative, emetic, tonic, anti-phlogistic, aphrodisiac and anti-ophthalmic agents. The purpose of the present investigation was to study antioxidant, anti-inflammatory and analgesic activity of Abrus precatorius Linn. ethanolic seed extracts by soxhlet method. The free radical scavenging activity of extract was carried out by 1,1-diphenyl-2-picrylhydrazyl method and anti-inflammatory activity by carrageenan induced rat paw edema and analgesic activity carried out by tail flick and tail immersion method. The extract showed significant activity i.e., 80.1±0.34% at 300 μg mL-1. The extract was evaluated for its anti-inflammatory activity it showed significant anti-inflammatory activity i.e., 62.68% at 375 mg kg-1 by carrageen induced method. Further, the extract was evaluated for analgesic activity and the extract showed significant activity at 300 mg kg-1 after 90 min interval by tail flick and tail immersion method. As ethanolic extract of Abrus precatorius Linn. was found to have potent antioxidant, anti-inflammatory and analgesic potential. The present study concludes that seeds of Abrus precatorius Linn. can be used as good natural antioxidant to treat free radical induced disease.
  Naresh Singh Gill , Ramandeep Kaur , Rashmi Arora and Manoj Bali
  Use of plants for health benefits is widespread in India. The present study was to investigate ethanolic seed extract of Caesalpinia crista for antioxidant activity by 1,1-diphenyl-2-picryl hydrazyl and hydrogen peroxide methods and anti inflammatory by Carrageenan induced paw edema and analgesic activity by writhing reflexes and by tail immersion method in mice. The extract showed potent antioxidant activity i.e., 73.9 and 77.7% at 300 μg mL-1 by 1,1-diphenyl-2-picryl hydrazyl and hydrogen peroxide method as compared to the standard (ascorbic acid). Further, the extract was evaluated for anti inflammatory activity and the extract showed maximum inhibition of 74.2% at 300 mg kg-1 by Carrageenan induced paw edema method as compared to standard (diclofenac). Furthermore, the extract was evaluated for analgesic activity the extract showed potent analgesic activity i.e., 71% at 300 μg mL-1 by writhing reflexes in mice and the tail withdrawal latency of mice was 5.30±0.05 sec at 300 μg mL-1 by tail immersion method. The present study concludes that Caesalpinia crista seeds have potent antioxidant, anti inflammatory and analgesic activity it can be used for therapeutic potential.
 
 
 
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