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Articles by Nur Indrawaty Lipoeto
Total Records ( 3 ) for Nur Indrawaty Lipoeto
  Nurhayati , Nuzulia Irawati , Eryati Darwin and Nur Indrawaty Lipoeto
  Background and Objective: Geohelminth is a common cause of chronic infections in humans. Worm infections have been shown to have a protective effect against some diseases. The effect is related to the ability of the worm to modulate the host immune response through Th2. The aim of study was to investigate the correlation between IL-10 levels and blood cholesterol and glucose in geohelminth positive human subjects with mature immune systems. Materials and Methods: Stool examination for geohelminth was done by direct method using iodine and by Kato Katz method. IL-10 levels were measured by indirect enzyme-linked immunosorbent assays (ELISA) method. Total plasma cholesterol levels were examined by CHOD-PAP method and fasting blood glucose was measured using hexokinase method. Results: All subjects infected with geohelminth classified as a mild infection. There was no correlation between IL-10 levels and EC/GC (p>0.05) but there was a negative correlation between IL-10 levels with TC levels (p<0.01) and between IL-10 levels and FBG levels (p<0.01). Conclusion: A negative correlation between IL-10, TC and FBG further strengthens support for the role of Th2 especially IL-10 to low cholesterol and blood glucose levels in geohelminth infections.
  Nila Kasuma , Fadil Oenzil and Nur Indrawaty Lipoeto
  Gingivitis is a disease affecting the gingival tissues, when the gingivitis is not properly treated, it will lead to a destructive of periodontal tissue structure. Periodontitis can cause periodontal tissue destruction and loss of the dental arch, further facial abnormalities and gastrointestinal disorder. Zinc is Matrix Metalloproteinase-8 cofactor. This study aims to prove the relationship between levels of Matrix Metalloproteinase-8 of the Gingival Crevicular Fluid (GCF) and zinc consumption of the Minangkabaunese in West Sumatera, Indonesia. This study involved 60 subjects, consisted of 20 healthy subjects, 20 patients of mild gingivitis and 20 patients of mild periodontitis. Matrix Metalloproteinase-8 level was tested by using ELISA method. Consumption of zinc was measured by using Minangkabau Food Frequency Questionnaire (FFQ). Data analysis was performed by means of univariate to describe each variable. Kolmogorov Smirnof Test was used to analyze normal distribution. Pearson correlation was applied to correlate between Matrix Metalloproteinase-8 level and zinc consumption. This study concluded that there was a significant correlation between the levels of matrix metalloprotease-8 and zinc consumption. Relationship between Matrix Metalloproteinase-8 and zinc consumption showed a strong correlation with negative direction (r = -0.865). Supplementation of zinc maybe used as a treatment for periodontal inflammation.
  Masrul , Eva Decroli , Idral Purnakarya and Nur Indrawaty Lipoeto
  Diabetes Mellitus type-2 is a chronic degenerative disease with an increasing prevalence and incidence rate. Obesity and insulin resistance have been confirmed as the main causes. This study aims to understand the effect of modified diet and exercise to insulin level in diabetes mellitus type-2 patients. This was a comparative experimental study to modify body weight in diabetes mellitus type-2 patients with obesity in a diabetic clinic of Dr. M Djamil Hospital, from January until December 2010. Subjects in the treatment group received the consultation regarding exercise and modified diet for six months whereas subjects in the control group did not get any intervention. Then, in the end of the study, the BMI, fasting glucose and insulin level were measured in both groups. We found a significant difference in protein intake in both groups. We also found a significant difference in insulin level before and after the treatment (12.24±9.21 μU/ml and 8.58±4.40 μU/ml; p = 0.035, respectively). There is no significant difference in reduction of blood glucose level in both groups. We suggest to further research to see the role of glycemic index to blood glucose level in diabetes mellitus type-2 patients and distribution of information in community about the role of modified diet and exercise to reduce obesity in diabetes patients.
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