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Articles by Ming-Chang Zhu
Total Records ( 1 ) for Ming-Chang Zhu
  En-Jun Gao , Ying Zhang , Lin Lin , Ren-Shu Wang , Lei Dai , Qi Liang , Ming-Chang Zhu , Mei-Lin Wang , Lei Liu , Wen-Xuan He and Yan-Jin Zhang
  Two manganese complexes, [Mn(L1)2(dibe)2](L1) (1) and [Mn(L2)(dibe)2] (2) (where L1 = 2,2′-bipyridine (bipy), L2 = 1,10-phenanthroline (phen)), were synthesized by using a carboxylic acid ligand (dibe = 2,2-dibenzylmalonate acid). The two complexes were characterized using IR, elemental analysis, and X-ray crystallography. Fluorescence analysis indicates that the two complexes can bind to HeLa cell DNA (HC-DNA), and gel electrophoresis assay demonstrates the ability of the complexes to cleave the HC-DNA. The two complexes exhibit cytotoxic specificity and significant cancer cell inhibitory rate. Furthermore, apoptotic tests demonstrate that these two complexes have apoptotic effects on HeLa cells.
 
 
 
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