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Articles by Fei Gao
Total Records ( 5 ) for Fei Gao
  Jiegui Wang , Li Wu , Fei Gao , Chao Gao and Xinyuan Wang
  From an interdisciplinary point of view, this article discusses the application of a remote sensing environmental archaeology method in the study of ancient settlements by investigating the development and revolution of archaeology as well as the idea of remote sensing environmental archaeology. The study proposes a new method of multi-source information composition of remote sensing environmental archaeology to identify ancient settlements under the support of spatial analysis. Based on the characteristics of ancient settlements and their spatial relationship with their surroundings, remote sensing image recognition and geospatial analysis are applied to obtain the multi-source information composition of remote sensing environmental archaeology and then effectively determine the existence and the location of ancient settlements. In combination with field validation, the identification can be achieved. Based on the discussions, the technological integration of the remote sensing environmental archaeology method and its future application in the archaeology of ancient settlements are further explored.
  Jiemin Pan , Fei Gao , Yuqian Bao , Lei Zhang , Yinfang Tu and Weiping Jia
 

Background

Urinary albumin excretion rate (UAER) is a remarkable index reflecting the progression of kidney disease in diabetic subjects. The link between UAER and lipid metabolism is still unclear. The correlation of Apolipoprotein B (ApoB) to albuminuria has been investigated. The National Cholesterol Education Program-Adult Treatment Panel III recommends that clinicians consider non-high-density lipoprotein cholesterol (non-HDL-c) as a surrogate marker for ApoB.

Objective

We sought to evaluate the relationship of UAER with lipid profile, especially with non-HDL-c in type 2 diabetic patients without renal dysfunction.

Methods

A total of 507 type 2 diabetic patients with normal renal function participated in this study. Demographic and anthropometric data were collected; 24-hour urine samples were collected for UAER measurement. Blood samples were collected for lipid parameters and HbA1c measurement.

Results

The patients with albuminuria had greater levels of non-HDL-c and ApoB. The frequencies of albuminuria among the four quartiles of lipid parameters, ie, triglycerides, total cholesterol, non-HDL-c, and ApoB, demonstrated significantly linearly increasing (P for trend <.01). After adjustment, UAER was significantly correlated with total cholesterol, triglycerides, ApoB, and non-HDL-c but not with low-density lipoprotein cholesterol (LDL-c) or lipoprotein(a) [Lp(a)]. Stepwise regression analysis showed that age (β = .255, P = .000), systolic blood pressure (β = .261, P = .000), non-HDL-c (β = .164, P = .000), and duration of diabetes (β = .105, P = .024) were independently correlated with UAER in diabetic patients without renal dysfunction.

Conclusion

Compared with the lipid parameters of total cholesterol, triglycerides, HDL-c, LDL-c, ApoB, Apolipoprotein A-I (ApoA-I), and Lp(a), non-HDL-c was more closely associated with albuminuria in Chinese type 2 diabetic patients without impaired renal function.

  Jiandong Mao , Dengxin Hua , Yufeng Wang , Fei Gao and Li Wang
  An ultraviolet rotational Raman lidar (RRL) system at an eye-safe wavelength of 354.7 nm is demonstrated for profiling the vertical temperature of the atmospheric layer. Two sets of narrow-band interference filters, which central wavelengths are located at 353.9 and 352.5 nm, respectively, are employed to block the elastic Mie- and Rayleigh-scattering signals and to separate two required rotational Raman signals for temperature retrieval. Experiments were carried out for verifying the feasibility of the prototype of the ultraviolet RRL from May to November in 2008, and the system calibrations were performed with the radiosonde data which were obtain from the local meteorological bureau, and good agreements were got in the experiment results. The observation results show that a statistical temperature error of less then 1 K was obtained up to the heights of 2.5 km for nighttime and 2.0 km for daytime with 300 mJ laser energy and not, vert, similar8 min observation time.
  Jinshu Wang , Wei Liu , Fei Gao , Zhiyuan Ren and Meiling Zhou
  La2O3–Mo, Y2O3–Mo, Gd2O3–Mo and Ce2O3–Mo were prepared by liquid–liquid doping combined with spark plasma sintering. The microstructure and surface behaviour of rare earth oxide of the cathode have been studied by microscope, Auger Electron Spectroscopy (AES) and X-ray Photoelectron Spectroscopy (XPS) methods. Among these four kinds of cathode, Y2O3–Mo cathode exhibits the best secondary emission property, i.e., the maximum secondary emission yield could reach 5.24. The penetration depth of primary electrons and escape depth of secondary electrons have been calculated and the energy distribution of primary electrons in the cathode has been simulated by Monte Carlo method. Y2O3–Mo cathode has the largest penetration depth and escape depth, which could be attributed to the highest secondary electron emission yield of the cathode.
  Fei Gao , Jeffrey R. Koenitzer , Jacob M. Tobolewski , Dianhua Jiang , Jiurong Liang , Paul W. Noble and Tim D. Oury
  Extracellular superoxide dismutase (EC-SOD) is expressed at high levels in lungs. EC-SOD has a polycationic matrix-binding domain that binds to polyanionic constituents in the matrix. Previous studies indicate that EC-SOD protects the lung in both bleomycin- and asbestos-induced models of pulmonary fibrosis. Although the mechanism of EC-SOD protection is not fully understood, these studies indicate that EC-SOD plays an important role in regulating inflammatory responses to pulmonary injury. Hyaluronan is a polyanionic high molecular mass polysaccharide found in the extracellular matrix that is sensitive to oxidant-mediated fragmentation. Recent studies found that elevated levels of low molecular mass hyaluronan are associated with inflammatory conditions. We hypothesize that EC-SOD may inhibit pulmonary inflammation in part by preventing superoxide-mediated fragmentation of hyaluronan to low molecular mass fragments. We found that EC-SOD directly binds to hyaluronan and significantly inhibits oxidant-induced degradation of this glycosaminoglycan. In vitro human polymorphic neutrophil chemotaxis studies indicate that oxidative fragmentation of hyaluronan results in polymorphic neutrophil chemotaxis and that EC-SOD can completely prevent this response. Intratracheal injection of crocidolite asbestos in mice leads to pulmonary inflammation and injury that is enhanced in EC-SOD knock-out mice. Notably, hyaluronan levels are increased in the bronchoalveolar lavage fluid after asbestos-induced pulmonary injury, and this response is markedly enhanced in EC-SOD knock-out mice. These data indicate that inhibition of oxidative hyaluronan fragmentation probably represents one mechanism by which EC-SOD inhibits inflammation in response to lung injury.
 
 
 
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