Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies

K. S Peggs, S. A Quezada, C. A Chambers, A. J Korman and J. P. Allison

The Journal of Experimental Medicine 206 ( 8 ): 1717 - 1725 , 2009