Abstract: Bishops weed-Ammi majus L. (Apiaceae) is one of the richest natural sources of linear coumarins and furanocoumarins; umbelliferone, psoralen, xanthotoxin, bergapten and imperatorin and having great medicinal value. The fruit of A. majus has been used in the Mediterranean and bordering regions in the treatment of leucoderma, psoriasis, vitiligo and now a days in cancer and AIDS treatments also. Clay pot culture was conducted to know the response of plant to salt stress, growth and biochemical responses and nutrients uptake in different soil sodicity. The results showed inhibited growth responses with increasing sodicity of soil. Also, decrease in chlorophyll contents a, b and carotenoid contents were also observed. Further changes in the activities of catalase were obtained. On contrary a reverse trend for peroxidase was observed in leaves with increased ESP levels. Sodium content in plants was increased, while potassium and zinc was decreased in different parts of plant with increase in the soil sodicity. Copper varied differently in different plant parts of plant. These observations showed the inhibition in the growth responses due to sodicity stress.