Abstract: Nutraceuticals have received considerable interest because of their presumed safety and potential nutritional and therapeutic effects. Pharmaceutical and nutritional companies are aware of the monetary success taking advantage of the more health-seeking consumers and the changing trends resulting in a proliferation of these value-added products aimed at heart health to cancer. Majority of the nutraceuticals are claimed to possess multiple therapeutic benefits though substantial evidence is lacking for the benefits as well as unwanted effects. The present review has been devoted towards better understanding of the nutraceuticals based on their disease specific indications.